Browse > Article

Radiographic Estimation of Colonic Transit Time with $Kolomark^{TM}$ in Normal Dogs  

Cho, Young-Kwon (Department of Radiological Technology, Daegu Health college)
Kim, Sun-Chil (Department of Radiological Technology, Daegu Health college)
Lee, Ki-Chang (College of Veterinary Medicine, Chonbuk National University)
Publication Information
Journal of Veterinary Clinics / v.29, no.3, 2012 , pp. 237-241 More about this Journal
Abstract
Colonic transit time plays an important role in creating a disease category and treatment plan in patients with chronic constipation or bowel movement problem. The aim of this study is to establish normal colon transit time using Kolomark, a radiopaque marker in dogs. The transit time of Kolomark in colon was measured every 2, 4, 8, 12, 24, 48 hours in 11 healthy Beagle dogs with oral administration of the marker. Kolomark began to appear in colon after 4 hours from administration and the largest number of Kolomark in colon was observed after 12 hours. Then, after 24 hours, some quantity of Kolomark was found but Kolomarks were all eliminated from the colon after 48 hours. The mean emptying time of Kolomark was 28.36 hours. Based on this study, the normal range of colon transit time in dogs was established by using the Kolomark, and it could be used as reference data for objective evaluation of constipation in canine patients.
Keywords
colon transit time; dog; constipation; Kolomark;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Park IS, Lee HR, Lee SI, Kim KW, Lee SM, Cho JS, Pack HJ, Choi JY, Cho HS. Contributing factors of colonic transit time in normal adults. Korean J Gastroenterol 1999; 34: 330-337.
2 Roe IH, Jung HC, Kim SY, Lee HS, Yoon YB, Song IS, Choi KW, Kim CY. Colonic transit time in chronic idiopathic constipation and diabetic congestipation. Kor J Med 1990; 39: 620-629.
3 Sung IK, Rhee PL, Jeon SK, Shim SG, Son HJ, Kim JJ, Koh KC, Paik SW, Rhee JC, Choi KW, Lim HK. Effect of Total Dietary Fiber on Bowel Habit and Bowel Transit in Healthy Subjects. Korean J Gastroenterol 2000; 35: 39-45.   DOI   ScienceOn
4 Tuleu C, Andrieux C, Boy P, Chaumeil JC. Gastrointestinal transit of pellets in rats: effect of size and density. Int J Pharm 1999; 180: 123-131.   DOI   ScienceOn
5 Zaslavsky C, da Silveira TR, Maguilnik I. Totaland segmental colonic transit time with radio-opaque markers in adolescents with functional constipation. J Pediatr Gastroenterol Nutr 1998; 27: 138-142.   DOI   ScienceOn
6 Charles F, Camillei M, Phillips SF, Thomforde GM, Forstrom LA. Scintigraphy of the whole gut: clinical evaluation of transit disorders. Mayo Clin Proc 1995; 70: 113-118.   DOI   ScienceOn
7 Choi H, Choi MG, Kim BW, Kim JK, Han SW, Choi KY, Chung KW, Sun HS, Par, DH, Son HS. Segmental Colon Transit Time with Radiopaque Makers in a Delayed-release Capsule. Kor J Neurogastroenterol Motil 1999; 5: 198-206.
8 Choi SC, Kim JH, Hwang HG, Yang SH, Kim JA, Nah YH, Lee CH, Kim CG. Scintigraphic Measurement of Regional Colonic Transit Time in Healthy Controls. Korean J Gastroenterol 1997; 29: 1-8.
9 Chung MG, Song CW, Moon JS, Jeen YT, Um SH, Kim CD, Ryu HS, Hyun JH. Effects of psyllium husk on slow transit constipation. Korean J Gastroenterol 1996; 28: 513-519.
10 Cummings JH, Jenkins DJ, Wiggins HS. Measurement of the mean transit time of dietary residue through the human 9ut. Gut 1976; 17: 210-218.   DOI   ScienceOn
11 Cummings JH, Wiggins HS. Transit through the gut measured by analysis of a single stool. Gut 1976; 17: 219-223.   DOI   ScienceOn
12 Degen LP, Phillips SF. How well does stoolform reflect colonic transit? Gut 1996; 39: 109-113.   DOI   ScienceOn
13 Degen LP, Phillips SF. Variability of gastrointestinaltransit in healthy women and men. Gut 1996; 39: 299-305.   DOI   ScienceOn
14 Halls J. Bowel content shift during normal defaecation [summary]. Proc R Soc Med 1965; 58: 895-60.
15 Hinton JM, Lennard-Jones JE, Young AC. A new method for studying gut transit times using radiopaque markers. Gut 1969; 10: 842-847.   DOI   ScienceOn
16 Hammer J, Phillips SF. Fluid loading of the human colon: effects on segmental transit and stool composition. Gastroenterology 1993; 105: 988-998.   DOI
17 Hansky J, Connell AM. Measurement of gastrointestinal transit using radioactive chromium. Gut 1962; 3: 187-188.   DOI   ScienceOn
18 Hinds JP, Stoney B, Wald A. Does gender or the menstrual cycle affect colonic transit? Am J Gastroenterol 1989; 84: 123-126.
19 Kim JE, Rhee PL, Kim YH, Sung IK, Shim SG, Son HJ, Kim JJ, Koh KC, Paik SW, Rhee JC, Choi KW, Lim HK, Suh SW. The development of kolomarkTM, a Korean radioopaque marker for measuring colon transit time. Kor J Neurogastroenterol Motil 1999 Dec; 5: 151-155.
20 Kim JW, Chung KS. Colonic Transit Time in Children with Recurrent Abdominal Pain. Korean J Pediatr 1997; 40: 1544-1551.
21 Madsen JL. Effects of gender, age, and bodymass index on gastrointestinal transit times. Dig Dis Sci 1992; 37: 1548-1553.   DOI   ScienceOn
22 Martelli H, Devroede G, Arhan P, Duguay C, Faverdin C. Some parameters of large bowel motility in normal man. Gastroenterology 1978; 75: 612-618.
23 Metcalf AM, Phillips SF, Zinsmeister AR, MacCarty RL, Beart RW, Wolff BG. Simplified assessment of segmental colon transit. Gastroenterology 1987; 92: 40-47.   DOI
24 Ashraf W, Park F, Lof J, Quigley EM. An examination of the reliability of reported stool frequency in the diagnosis of idiopathic constipation. Am J Gastroenterol 1996; 91: 26-32.
25 Bruce SJ, Guiford WG, Hedderley DI, McGauley M. Development of reference intervals for the large intestinal transit of radiopaque markers in dogs. Vet Radiol Ultrasound 1999; 40: 472-476.   DOI
26 Becker U, Elsborg L. A new method for the determination of gastrointestinal transit times. Scand J Gastroenterol 1979; 14: 355-359.   DOI   ScienceOn