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A Retrospective Study of 94 Hypercalcemic Dogs(2002-2004)  

Cho, Tae-Hyung (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Kang, Byeong-Teck (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Park, Chul (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Jung, Dong-In (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Yoo, Jong-Hyun (BK21 Program of Intergrative Network Systems for Veterinarians in Basic Science Industrial Animals and Preventive Medicines, College of Veterinary Medicine, Konkuk University)
Kim, Ju-Won (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Kim, Ha-Jung (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Lim, Chae-Young (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Lee, So-Young (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Kim, Jung-Hyun (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Woo, Eung-Je (College of Electronics and Information, Kyunghee University)
Park, Hee-Myung (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Publication Information
Journal of Veterinary Clinics / v.24, no.4, 2007 , pp. 479-485 More about this Journal
Abstract
A retrospective study of 94 hypercalcemic dogs was performed to find out most common causes that lead to hypercalcemia through investigating dogs referred to the Veterinary Teaching Hospital of Konkuk University from 2002 to 2004. During the study period, hypercalcemia was found in 94 dogs of 19 breeds, and they were evaluated as case group. Control group was made up of 94 dogs of 18 breeds without hypercalcemia admitted for the same study period. For general signalments, there were no significant differences between case and control group with the exception of age distribution. Shih-tzu(17.02%) and Yorkshire terrier(26.60%) was the most common breed in case and control group, respectively. The most common diseases associated with hypercalcemia were chronic renal failure (18.09%), acute renal failure(14.89%), and renal calculi(6.38%). Malignant neoplasia(lymphoma, hemangiosarcoma, chronic lymphocytic leukemia, mammary gland tumor, and multiple myeloma) and endocrinopathies(hyperadrenocorticism, hyperthyroidism, hypoadrenocorticism, and hypothyroidism) occupied 8.5% and 6.4%, respectively. This report is a first retrospective study of hypercalcemic dogs in South Korea.
Keywords
dog; hypercalcemia; retrospective study;
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1 Priester WA, McKay FW. The occurrence of tumors in domestic animal. J Natl Cancer Inst 1980; 54: 1-210
2 Chew DJ, Meuten DJ. Disorders of calcium and phosphorous metabolism. Vet Clin North Am Small Anim Pract 1982; 12: 411-438   DOI
3 Lauel EW, John MG, Richard KD, Jeffrey LJ, Rance MG, Douglas HT, Susan EL, Mary S, Antony SM. Carcinoma of the apocrine glands of the anal sac in dogs: 113 cases (1985-1995). J Am Vet Med Assooc 2003; 223: 825-831   DOI   ScienceOn
4 Meuten DJ, Chew DJ, Capen CC, Kociba GJ. Relationship of serum total calcium to albumin and total protein in dogs. J Am Vet Med Assoc 1992; 180: 63-67
5 Rosol TJ, Chew DJ, Nagode LA, Capen CC. Pathophysiology of calcuim metabolism. Vet Clin Pathol 1995; 24: 49-63   DOI   ScienceOn
6 Ruslander DA, Gebhard DH, Tompkins MB, Grindem CB, Page RL. Immunophenotypic characterization of canine lymphoproliferative disorders. In Vivo 1997; 11: 169-172
7 Willard MD, Schall WD, McCaw DE, Nachreiner RF. Canine hypoadrenocorticism: report of 37 cases and review of 39 previously reported cases. J Am Vet Med Assoc 1982; 180: 59-62
8 Sarah JL, Mark CW, Robert LG. Unusual IgM-secreting multiple myeloma in a dog. J Am Vet Med Assooc 2003; 223: 645-648   DOI   ScienceOn
9 Kruger JM, Osborne CA, Nachreiner RF, Refsal KR. Hypercalcemia and renal failure. Etiology, pathophysiology, diagnosis, and treatment. Vet Clin North Am Small Anim Pract 1996; 26: 1417-1445   DOI
10 Mellanby RJ, Mee AP, Berry JL, Herrtage ME. Hypercalcaemia in two dogs caused by excessive dietary supplementation of vitamin D. J Small Anim Pract 2005; 46: 334-338   DOI   ScienceOn
11 Uehlinger P, Glaus T, Hauser B, Reusch C. Hypercalcemia in dogs – A retrospective study of 46 cases. Schweiz Arch Tierheilkd 1998; 140: 188-197
12 Teske E, van Heerde P, Rutteman GR, Kurzman ID, Moore PF, MacEwen EG. Prognostic factors for treatment of malignant lymphoma in dogs. J Am Vet Med Assoc 1994; 205: 1722-1728
13 Ebashi S. $Ca^{2+}$ in biological systems. Experientia 1985; 41: 978-981   DOI   ScienceOn
14 O'Brien TD, Osborne CA, Yano BL, Barnes DM. Clinicopathologic manifestations of progressive renal disease in Lhasa Apso and Shih Tzu dog. J Am Vet Med Assoc 1982; 180: 658-664
15 Chew DJ, Capen CC. Calcium nephropathy and associated disorders. In: Kirk's Current veterinary therapy, VII 7th ed. Philadelphia: W. B. Saunders. 1980: 1067-1072
16 Meuten DJ. Hypercalcemia. Vet Clin North Am Small Anim Pract 1984; 14: 891-910   DOI
17 Chew DJ, Carothers M. Hypercalcemia. Vet Clin North Am Small Anim Pract 1989; 19: 265-287   DOI
18 Nelson RW, Turnwald GH, Willard MD. Endocrine, metabolic, and lipid disorders. In: Small animal clinical diagnosis by laboratory methods. 4th ed. St. Louis: W. B. Saunders. 2004: 166-167
19 Onions DE. A prospective survey of familial canine lymphosarcoma. J Natl Cancer Inst 1984; 72: 909-912
20 Rosol TJ, Capen CC. Pathophysiology of calcium, phosphorus, and magnesium metabolism in animals. Vet Clin North Am Small Anim Pract 1996; 26: 1155-1184   DOI
21 Vail DM, MacEwen EG, Young KM. Canine lymphoma and lymphoid leukemias. In: Small animal clinical oncology, 3rd ed. Philadelphia: W. B. Saunders. 2001: 558-590
22 Weir EC, Burtis WJ, Morris CA. Isolation of 16,000 dalton parathyroid hormone like proteins from two animal tumors causing humoral hypercalcemia of malignancy. Endocrinology 1988; 123: 2744-2751   DOI   ScienceOn
23 Berger B, Feldman FC. Primary hyperparathyroidism in dogs: 21 cases (1976-1986). J Am Vet Med Assoc 1987; 191: 350-356
24 Martin LG. Hypercalcemia and hypermagnesemia. Vet Clin North Am Small Anim Pract 1998; 28: 565-585   DOI
25 Peterson ME, Feinman JM. Hypercalcemia associated with hypoadrenocorticism in sixteen dogs. J Am Vet Med Assoc 1982; 181: 802-804