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An Antioxidant Homo-Flavoyadorinin-B from Korean Mistletoe (Viscum album var. coloratum)  

Choi, Seung-Young (Division of Applied Biology & Chemistry, Kyungpook National University)
Chung, Shin-Kyo (Department of Food Science & Technology, Kyungpook National University)
Kim, Suk-Kyung (Department of Food Science & Technology, Kyungpook National University)
Yoo, Yung-Choon (School of Medicine, Konyang University)
Lee, Kyung-Bok (School of Medicine, Konyang University)
Kim, Jong-Bae (Department of Biotechnology & Food Science, Handong University)
Kim, Ja-Young (Division of Applied Biology & Chemistry, Kyungpook National University)
Song, Kyung-Sik (Division of Applied Biology & Chemistry, Kyungpook National University)
Publication Information
Applied Biological Chemistry / v.47, no.2, 2004 , pp. 279-282 More about this Journal
Abstract
An antioxidant was isolated from Korean mistletoe (Viscum album var. coloratum) by consecutive purification using silica gel, Sephadex LH-20, and RP-HPLC. The active principle was identified as homo-flavoyadorinin-B (3',7-dimethoxyluteolin-4'-O-[apiosyl $(1{\rightarrow}2)$ glucoside]) by spectral analyses. It inhibited 74.6% of hydroxyl radical and 30.6% of superoxide anion radical at 0.01 mM; however, th~compound did not show any scavenging activity against hydrogen peroxide radical. At 0.1 mM, above compound scavenged superoxide anion radical about twice as effective as positive controls, BHT and ${\alpha}-tocopherol$. Radical scavenging activities of homo-flavoyadorinin-B on DPPH, hydroxyl, and hydrogen peroxide radicals were almost same with those of positive controls.
Keywords
Viscum album var. coloratum; reactive oxygen species scavenger; antioxidant; homo-flavoyadorinin-B;
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