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http://dx.doi.org/10.9718/JBER.2007.28.4.556

Analysis of the Likelihood of Successful Defibrillation as a Change of Cardiopulmonary Resuscitation Transition using Support Vector Machine  

Jang, Seung-Jin (Department of Bimomedical Engineering, Health and Science College, Yonsei University)
Hwang, Sung-Oh (Department of Emergency Medicine, Wonju College of Medicine, Yonsei University)
Lee, Hyun-Sook (Department of Oriental Biomedical Engineering, College of Health Science, Sangji University)
Yoon, Young-Ro (Department of Bimomedical Engineering, Health and Science College, Yonsei University)
Publication Information
Journal of Biomedical Engineering Research / v.28, no.4, 2007 , pp. 556-568 More about this Journal
Abstract
Unsatisfied results of return of spontaneous circulation (ROSC) estimates were caused by the fact that the predictability of the predictors was insufficient. This unmet estimate of the predictors may be affected by transitional events due to behaviors which occur during cardiopulmonary resuscitation (CPR). We thus hypothesized that the discrepancy of ROSC estimates found in statistical characteristics due to transitional CPR events, may affect the performance of the predictors, and that the performance of the classifier dichotomizing between ROSC and No-ROSC might be different during CPR. In a canine model (n=18) of prolonged ventricular fibrillation (VF), standard CPR was provided with administration of two doses of epinephrine 0 min or 3 min later of the onset of CPR. For the analysis of the likelihood of a successful defibrillation during CPR, Support Vector Classification was adopted to evaluate statistical peculiarity combining time and frequency based predictors: median frequency, frequency band-limited power spectrum, mean segment amplitude, and zero crossing rates. The worst predictable period showed below about 1 min after the onset of CPR, and the best predictable period could be observed from about 1.5 min later of the administering epinephrine through 2.0-2.2 min. As hypothesized, the discrepancy of statistical characteristics of the predictors was reflected in the differences of the classification performance during CPR. These results represent a major improvement in defibrillation prediction can be achieved by a specific timing of the analysis, as a change in CPR transition.
Keywords
ventricular fibrillation; cardiopulmonary resuscitation (CPR); return of spontaneous circulation (ROSC); support vector classification (SVC);
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