1 |
Kirchheiner J, Nickchen K, Bauer M, Licinio J, Wong M-L, Roots I, Brockmoller J. Therapeutic implications from pharmacogenetics in antidepressant and antipsychotic drug therapy. Mol Psychiatry (in press)
|
2 |
La Du B.N.(1992): Human serum paraoxonase/arylesterase. In Kalow, W.(ed.): Pharmacogenetics of Drug Metabolism. New York; Pergamon Press, pp51-91
|
3 |
Lesko, L.J. et al. (2003) Pharmacogenetics and pharmacogenomics in drug development and regulatory decision making: report of the first FDA-PWG-PhRMA-DruSafe Workshop. J. Clin. Pharmacol. 43, 342-358 84
|
4 |
Funk, C., Pantze, M., Jehle, L., Ponelle, C., Scheuermann, G., Lazendic, M., Gasser, R.(2001).Troglitazone-induced intrahepatic cholestasis by an interference with the hepatobiliary export of bile acids in male and female rats. Correlation with the gender difference in troglitazone sulfate formation and the inhibition of the canalicular bile salt export pump (Bsep) by troglitazone and troglitazone sulfate. Toxicology. 167, 83-98
DOI
ScienceOn
|
5 |
Bracco, L. and Kearsey, J. (2003) The relevance of alternative RNA splicing to pharmacogenomics. Trends Biotechnol. 21, 346-353
DOI
ScienceOn
|
6 |
Evans W.E.(1999) Pharmacogenomics: Translating functional genomics into national therapeutics. Science 286, 487-491
DOI
ScienceOn
|
7 |
Fukushima-Uesaka, H. et al. (2004) Haplotypes of CYP3A4 and their close linkage with CYP3A5 haplotypes in a Japanese population. Hum. Mutat. 23, 100
DOI
ScienceOn
|
8 |
Ingelman-Sundberg, M. (2004) Human drug metabolising cytochrome P450 enzymes: properties and polymorphisms. Naunyn Schmiedebergs Arch. Pharmacol. 369, 89-104
DOI
|
9 |
Kassahun, K., Pearson, P., Tang, W., McIntosh, I., Leung, K., Elmore, C., Dean, D., Wang, R., Doss, G., and Baillie, T.A. (2001). Studies on the metabolism of Troglitazone to reactive intermediates in vitro and in vivo. Evidence for novel biotransformation pathways involving quinone methide formation and Thiazolidinedione ring scission. Chem. Res. Toxicol. 14, 62-70
DOI
ScienceOn
|
10 |
Kaneko, A., Lum, J.K., Yaviong, J. (1999): High and variable frequencies of CYP2C 19 mutations: Medical consequences of poor drug metabolism in Vanuatu and other Pacific islands. Pharmacogenetics 9, 81-590
DOI
|
11 |
Lockridge, O. (1992): Genetic variants of human serum butyrylcholinesterase influence the metablolism of the muscle relaxant succinylcholine. In Kalow W.(ed.). Pharmacogenetics of Drug Metabolism. Pergamon Press. 15-50
|
12 |
Mayer U.(2000) Lancet 356, 1667
DOI
ScienceOn
|
13 |
Mayer U. Lancet 356:1667, 2000Meyer, W.A.(1994): The molecular basis of genetic polymorphisms of drug metabolism. J. Pharm. Pharmacol. 46, (Suppl. 1) 409-415
|
14 |
Pirmohamed, M. and Park, B.K. (2003) Cytochrome P450 enzyme polymorphisms and adverse drug reactions. Toxicology 192, 23-32
DOI
ScienceOn
|
15 |
Smith, G., Stubbins, M.J., Harris, L.W, Wolf, C.R.(1998): Molecular genetics of the human cytochrome P450 monooxygenase superfamily. Xenobiotica 8, 1129-1165
|
16 |
Spear, B.B. et al. (2001) Clinical application of pharmacogenetics. Trends Mol. Med. 7, 201-204
DOI
ScienceOn
|
17 |
Tucker, G.T. (1994): Clinical implications of genetic polymorphism in drug metabolism. J. Pharm. Pharmacol. 46(Suppl 1), 417-424
|
18 |
Yates C.R. et al. (1997) Molecular diagnosis of thiopurine Smethyltransferase deficiency:genetic basis for azathioprine and mercaptopurine intolerance. Ann. Intern. Med. 126, 60-614
|
19 |
Vatsis, K.P., Weber, W.W., Bell, D.A. et al.(2000): Nomenclature for N-acetyltransferases. Pharmacogenetics 10, 291-292
DOI
|
20 |
Weinshilboum, R. (2003) Inheritance and drug response. New Engl. J. Med. 348, 529-537
DOI
ScienceOn
|
21 |
Kato, R.. and Yamazoe, Y. (1994): The importance of substrate concentration in determing cytochrome P450 therapeutically relevant in vivo. Pharmacogenetics 4, 359-362
DOI
|
22 |
Ozdemir, V. et al. (2000) Evaluation of the genetic component of variability in CYP3A4 activity: a repeated drug administration method. Pharmacogenetics 10, 373-388
DOI
|
23 |
Yamamoto, Y., Yamazaki, H., Ikeda ,T., Watanabe, T., Iwabuchi, H., Nakajima, M., and Yokoi, T. (2002) Formation of a novel quinone epoxide metabolite of Troglitazone with cytotoxic to HepG2 cells. Drug Metab. Dispos, 30, 155-160
DOI
ScienceOn
|
24 |
Toyoda, Y., Tsuchida, A., Iwami, E., and Miwa, I., (2001): Toxic effect of troglitazone on cultured rat hepatocytes. Life Sci., 68, 1867-1876
DOI
ScienceOn
|
25 |
Van Schaik, R.H.N. et al. (2003) CYP3A4, CYP3A5 and MDR-1 variant alleles in the Dutch Caucasian population. Clin. Pharmacol. Ther. 73, 42
|
26 |
Phillips, K.A. et al. (2001) Potential role of pharmacogenomics in reducing adverse drug reactions: a systematic review. J. Am. Med. Assoc. 286, 2270-2279
DOI
ScienceOn
|