1 |
Roy, C.N., Penny, D.M., Feder, J.N., and Enns, C.A. (1999). The hereditary hemochromatosis protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells. Jounal of Biological Chemistry, 274, 9022-9028
DOI
|
2 |
Stearman, R., Yuan, D.S., Yamaguchi-Iwai, Y., Klausner, R.D., and Cancis, A. (1996). A pemiease-oxidase complex involved in high-affinity iron uptake in yeast. Science, 271, 1552-1557
DOI
ScienceOn
|
3 |
Liu, X.F. aiid Culotta, V.C. (1999). Post-translation control of Nramp metal transport in yeast. Role of meta1 ions and the BSD2 gene. J. Biol. Chem., 274, 4863-4868
DOI
ScienceOn
|
4 |
McMahom. R.J. and Cousins, R.J. (1998). Mammalian zinc transporters. Journal of Nutrition, 128, 667-670
|
5 |
Mercer, J.E, Livingston, J., Hall, B., Paynter, J.A., Begy, C., Chandrasekharappa, S., Lockhart, P., Grimes, A., Bhave, M and Siemieniak, D. (1993). Isolation of a partial candidate gene for Menkes disease by positional cloning. Nature Genetics, 3, 20-25
DOI
ScienceOn
|
6 |
Nclson, N. (1999). Mctal ion transportcrs and homeostasis. EMBO J. 18, 4361-4371
DOI
ScienceOn
|
7 |
Orgad, S., Nelson, H., Segal, D., and Nelson, N. (1998). Metal ions suppress tlie abnormal taste behavior of the Drosophila mutant malvolio. J. Exp. Biol., 201, 115-120
|
8 |
Palmiter, R.D., Cole, T.B., aiid Findley, S.D. (1996a). Znt-2, a mammalian protein that confers resistaiice to zinc by facilitaling vesicular seuestration. EMBO Jouranal, 15, 1784-1791
|
9 |
Palmiter, R.D., Cole, T.B., Quaife, C.J., and Findley, S.D. (1996b). ZnT-3, A putative transporter of zinc into xynaptic vesicles. Proceedings of the National Academy of Sciences of the USA, 93, 14934-14939
DOI
ScienceOn
|
10 |
Vidal, S., Belouchi, A.M., Cellier, M., Beatty, B., and Gros, P. (1995a). Cloning and characterizatioii of a second human Nramp gene on chromosome 12q13. Mammalian Genome, 6, 224-230
DOI
ScienceOn
|
11 |
Petrukhin, K., Lutsenko, S., Chernov, L., Ross, B.M., Kaplan, J.H., and Gilliam, T.C. (1994). Characterization of the Wilson disease gene encoding a P-type copper transporting ATPase genomic organization, altemative splicing, and structure/function predictions. Human Molecular Genetics, 3, 1647-1656
DOI
ScienceOn
|
12 |
Picard, V, Govoni, G., Jabado, N., and Gros, P. (2000). Nramp 2(DCT1/DMT1). Expressed at the plasma membrane transports iron and other divalent cations into a calcein accessible cytoplasmic pool. J. Biol Chem., 275, 35738-35745
DOI
ScienceOn
|
13 |
Radisky, D.C., Babcocok, M.C., and Kapkn, J. (1999). The yeast frataxin bomologue mediates mitochondrial iron efflux, Evidence for a mitochondrial iron cycle. Journal of Biological Chemistry, 274, 4497-4499
DOI
ScienceOn
|
14 |
Raja, K,B., Simpson, R..I., and Peters, T.J. (1992). Investigation of a role for reduction if ferric iron uptake by mouse duodenum. Biochimica et Biophysica Acta, 1135, 141-146
DOI
ScienceOn
|
15 |
Rensing, C., Mitra, B., and Rosen, B.P. (1997). The zntA gene of Escherichia uoli cncodes a Zn(II).-trans1ocation P-type ATPase. Proceedings of the National Academy of Sciences of the USA, 94, 14326-14331
DOI
ScienceOn
|
16 |
Rensing, C., Mitra, B., and Rosen, B.P. (1997). The zntA gene of Escherichia uoli cncodes a Zn(II).-trans1ocation P-type ATPase. Proceedings of the National Academy of Sciences of the USA, 94, 14326-14331
DOI
ScienceOn
|
17 |
Richardson, D.R. and Ponka, P. (1997). The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells. Biochimica et Biophysica Acfa, 1331, 1-40
DOI
ScienceOn
|
18 |
Zhao, H. and Eidc, D. (1996b). The ZRT2 gene encodes the low affmity zinc transporter in Saccharomyces cerevisiae. Journal of Biological Chemistry, 271, 23203-23210
DOI
ScienceOn
|
19 |
Tabuchi, M., Yoshmori, T., Yamaguchi, K. Yoshida, T., and Kishi, F. (2000). Human Nramp2/DMT1, Which mediates iron transport across endosomal mcmbranc, is localized to late endosomes and lysosomes m HEp-2 cells. J. Biol. Chem., 275, 22220-22228
DOI
ScienceOn
|
20 |
Tallkvist, J., Bowlus, C.L., and Lonnerdal, B. (2001). DMTl gene expression and cadmium absorption in human absorptive enterocytes. Toxicol. Lett., 122, 171-177
DOI
ScienceOn
|
21 |
Taiidy, S., Williams, M., Leggett, A., Lopez-Jimenez, M., Dedes, M., Ramesh, B., Srai, S.K., and Sharp, P. (2000). Nramp2 expression is associated with pH-dependent iron uptake across the apical membrane of human intestinal Caco2 cells. J. Biol. Chem., 275, 1023-1029
DOI
ScienceOn
|
22 |
Tanzi, R. E., Petrukhin, K., Chemov, L., Pellequer, J.L., Wasco, W., Ross, B., Romano, D. M., Parano, E., Pavone, L, and Brzustowicz, L.M. (1993). The Wilson disease gene is a copper transporting ATPase with homology to the Menkes diseasc gene. Nature Genetics, 5, 344-350
DOI
ScienceOn
|
23 |
Teichmannn, R. and Stremmel, W. (1990). lron uptake by human upper small intestinc microvillous membrane vesicles. Indication for a facilitated transport mechanism mediated by a membrane iron-binding protcin. Jounal of Clinical Investigation, 86, 2145-2153
DOI
|
24 |
Umbreit, J.N., Conrad, M.E., Moore, E.G., Dcsai, M.R, aiid Turrens, J. (1996). Paraferritin: a Protein complex with ferrireductasc activity is associated with iron absorption in rats. Biochemistry, 35, 6460-6469
DOI
ScienceOn
|
25 |
Van Eijk, H.G. and De Jong, G. (1992). The physiology of iron, transferrin, and ferritin. Biological Trace. Element Research, 35, 13-24
|
26 |
Vidal, S., Gros, R., and Skamene, E. (1995b). Natural resistance to infection with intracellular parasites: Molecular genetics identifies Nrampl as the Bcg/Ity/Lsh locus. Journal of Leukocyte Biology, 58, 382-390
|
27 |
Wien, E.M. and Van Campen, D.R. (1991). Ferric iron absoiption in rats: relationship to iron status, endogenous sulfhydiyl and other redox components in the intestinal lumen. Journal of Nutrition, 121, 825-831
|
28 |
Vidal, S., M., Malo, D., Vogan, K., Skamene, E., and Gros, P. (1993). Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg. Cell, 73, 469-485
DOI
ScienceOn
|
29 |
Vulpe, C., Levmson, B., Whitney, S., Packman, S., and Gitschiter, J. (1993). Isolation of a candidate gene of Menkes disease and evidence that it encodes a copper-transporting ATPase. Nature Genetics, 3, 7-13
DOI
ScienceOn
|
30 |
Wessling-Resnick, M. (2000). Iron transport. Annu. Rev. Nutr., 20, 129-151
DOI
ScienceOn
|
31 |
Williams, S.R. (1993). Minerals. In Nuthtion and Diet Thempy. pp. 220-268. Mosby-Year Book, St. Louis
|
32 |
Wilson, R.B. and Roof, D.M. (1997). Respiralory deficiency due to loss of mitochondrial DNA in yeast lacking the trataxin homologue. Nature Genetics, 16, 352-357
DOI
ScienceOn
|
33 |
Wood, R.J. and Han, O. (1998). Recent advanccs in nutritional science; Recently identified molecular aspects of intestinal iron absorption. J. Nutr., 128, 1841-1844
|
34 |
Zhao, H. and Eide, D. (1996a). The yeast ZRTl gene encodcs the zinc transporter protein of a high-affinity uptake system induced by zinc limitation. Proceedings of the National Academy of Sciences of the USA, 93, 2454-2458
DOI
ScienceOn
|
35 |
Zhou, B. and Gitschier, J. (1997). hCTRl-A human gene for copper uptake identified by complementation in yeast. Proceedings of the National Academy of Sciences of the USA, 94, 7481-7486
DOI
ScienceOn
|
36 |
Zwillmg, B.S., Kuhn, D.E., Wikoff; D.B., and Lafusc, W. (1999). Role of iron in Nramp 1-mediated inhibition of mycobacterial growth. Infection & Immunity, 67, 1386-1392
|
37 |
Belouchi, A., Kwan, T., and Gros, P. (1997). Cloning and characterization of the OsNramp family from Oiyza sativa, a new family of membrane proteins possibly implicated in the transport of metal ions. Plant Molecular Biotogy, 33, 1085-1092
DOI
ScienceOn
|
38 |
Bannon, D.I., Portony, M.E., Olivi, L. Lees, P.S.J. Culotta, V.C., and Bressler, J.P. (2002) Uptake of lead and iron by divalent metal transporter 1 in yeast and mammalian cells. Biocheniical and Biophysical Research Communication, , 978-984
DOI
ScienceOn
|
39 |
Barton, J.C., McDonnell, S.M., Adams, P.C., Bhssot, R, Powell, L.W., Edwards, C.Q., Cook, J.D, and Kowdley, K.V. (1998). Management of hemochromatosis. Hemochromatosis Management working group. Annals of Internal Medicine, 129, 932-939
DOI
ScienceOn
|
40 |
Bellamy, R., Ruwende, C., Corrah, T., McAdam, K.P., Whittle, H.C., and Hi1l, A.V. (1998). Variations in the Nrampl gene and susceptibility to tuberculosis in West Africans. New England Journal of Medicine, , 640-644
|
41 |
Canonne-Hergaux, Gruenheid, S. Ponka, P, and Gros, P. (1999). Cellular and subcellular localization of the Nramp2 iron transporter in the mtestinal brush border and regulation by dietary iron. Blood, 93, 4406-4417
|
42 |
Cohen, A., Nelson, H., and Nelson, N. (2000). The family of SMF metal ion transporters in Yeast cel1s. J. Biol. Chem., 275(43), 33388-33394
DOI
ScienceOn
|
43 |
Cole, T.B., wenzel, H.J., Kafei, K.E., Schwartzkroin, P.A., and Palmiter, R.D. (1999) Elimination of zinc from synaptic vesicles in fhe intact mouse braiii by disruption of the Zn T3 gene. Proc. Nati. Acad. Sci. U.S.A., 96, 1716-1721
DOI
ScienceOn
|
44 |
Agranoff, D.D. & Khshna, S. (1998). Metal ion homcostasis and intracellulair parasitism. Mol. Microbiol., 28, 403-412
DOI
ScienceOn
|
45 |
Conrad, M.E., Umbreit, J.N., Peterson, R.D., Moore, E.G., and Harper, K.P. (1993). Function of integrin in duodenal mucosal optake of iron. Blood, 81, 517-521
|
46 |
Dautry-Varsat, A., Ciechnover, A., and Lodish, H.F. (1983). Proc. Nati. Acad. Sci. U.S.A., 80,
DOI
ScienceOn
|
47 |
Dix, D.R,. Bridgham, J.T., Broderius, M.A. Byersdorfer, C.A., and Eide, D.J. (1994). The FET4 gene encodes the low affinity Fe(II). Transport protein of Saccharomyces cerevisiae. Journal of Biological Chemistry, 269, 26092-26099
|
48 |
Anderson, G.J., Murphy, T.L., Cowley, L., Evans, B.A., Halliday, J.W. & McLaren, G.D. (1998). Mapping the gene for sex-linked anemia-An inherited defect of intestinal iron absorption in the mouse. Genomics, 48, 34-39
DOI
ScienceOn
|
49 |
Andrews, N.C. (1999). The iron transporter DMT1.Int. J. Biochem. Cell Biol, 31, 991-994
|
50 |
Askwith, C.C. and Kaplan, J. (1998). Iron and copper transport in yeast and its relevance to human disease. Trends in Biochemical Sciences, 23, 135-138
DOI
ScienceOn
|
51 |
Babcock, M., de Silva, D., Oaks, R., Davis-Kaplan, S., Jiralerspong, S., Montermini, L., Pandolfo, M. and Kaplan, J. (1997). Regulation of mitochondrial iron accumulation by YfhlP, a putative homolog of grataxin. Science, 276, 1709-1712
DOI
ScienceOn
|
52 |
Farcich, E.A. and Morgan, E.H. (1992). Diminished iron acquisition by cells and tissues of Belgrade laboratory rats. Am. J. Physiol., 262, 220-224
|
53 |
Fleming, M.D., Romano. M.A., Su, M.A., Garrick, L.M., Garrick, M.D., and Andrews, N.C.(1998). Nramp2 is mutated in the anemic belgrade (b). rat: evidence of a role for Nramp2 in endosomal iron transport, Proceedings of the National Academy of Sciences of the USA, 95, 1148-1153
DOI
ScienceOn
|
54 |
Chelly, J., Tumer, Z., Tonnesen, T., Petterson, A., Ishikawa-Brush, Y., Tommerup, N., Horn, N, and Monaco, A. P. (1993). Isolation ofa candidate gene for Menkes disease that encodes a potential heavy metal binding protein. Nature Genetics, 3, 14-19
DOI
ScienceOn
|
55 |
Fleming, M.D., Trenor, C.C., Su, M.A., Foernzlei, D., Beier, D.R., Dietrich, W.E, and Andrews, N.C. (1997). Microcytic anaemia mice have mutation in Nramp2, a candidatc iron transporter gene. Nature Genetics, 16, 383-386
DOI
|
56 |
Fleming, R.E., Migas, M.C., Zhou, X., Jiang, J., Britton, R.S., Brunt, E.M., Tomatsu, S., Waheed, A., Baon, B.R., and Sly, W.S. (1999). Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: Increascd duodenal expression of the iron traspoter DMTl. Proceeding of the National Academy of Sciences of the USA, 96, 3143-3148
DOI
ScienceOn
|
57 |
Cellier, M., Phve, G., Belouchi, A., Kwan, T., Rodngues, V, Chia, W., and Gros, P. (1995). Nramp defines a family of membrane proteins. Proc. Nati. Acad. Sci. U.S.A., 92, 10089-10093
DOI
ScienceOn
|
58 |
Chen, X.Z., Peng, J.B., Cohen, A., Nelson, H., Nelson, N, and Hediger, M.A. (1999). Yeast SMFl mediates -coupled iron uptake with concomitant uncoupled cation currents. J. Biol. Chem., 274(49), 35089-35094
DOI
ScienceOn
|
59 |
Cheong, J.H. Bannon, D.I., Olivi, L. Kim, K, and Bressler, J.P. (2002) Transport of iron and lead in a rat glial cell line. J. Neurochemistry submitted
|
60 |
Gutierrez, J. A., Yu, J., and Wessling-Resnick, M. (1998). Characterization and chromosomal mapping of the acuman gene for SFT, a stimulator of Fe transport. Biochemical and Biophysical Research Communications, 253, 739-742
DOI
ScienceOn
|
61 |
Dorey, C., Cooper, C., Dickson, D.R, Gibson, J.E, Simpson, R.J., and Petters, T.J. (1993). Iron spedfication at physiological pH in media containing ascorbate and oxygen. British Journal of Nutrition, 10, 157-169
|
62 |
Gutierrez, J. A., Yu, J. M., Rivera, S., and Wessling-Resnick, M. (1997). Functional expression cloning aiid characterization of SFT, a stimulator of Fe transport. Journal of Cellular Biology, 139, 895-905
DOI
ScienceOn
|
63 |
Han, O., Failla, M.L., Hill, A.D., Morris, E.R., and Smith, J.C.J. (1995). Rcduction of Fe(III). is required for uptake of nonhcmc iron by Caco-2 cells. Journal of Nutrition, 125, 1291-1299
|
64 |
Han, O., FIeet, J.C., and Richard, J.W. (1995). Reciprocal regulation of HFE and Nramp2 gene expression by iron in human intestinal cells. Journal of Nutrition, 129, 98-104
|
65 |
Edwards, J.A. and Hoke, J.H. (1972). Defect of mtestinal mucosal iron uptake in mice with hereditary microcytic anemia. Proc. Soc. Exp. Biol. Med., 141, 81-84
DOI
|
66 |
Eide, D.J. (1998). The molecular biology of metal ion transport in Saccharomyces cerevisiae. Annual Review of Nutrition, 18, 441-469
DOI
ScienceOn
|
67 |
Eide, D., Brodeius, M,. Fett, J., and Guerinot, M.L. (1996). A novel iron-regulated metal transportcr from plants identificd by functional expression in yeast. Proceeding of the National Academy of Sciences of fhe USA, 93, 5624-5628
DOI
ScienceOn
|
68 |
Gac, G.L., Mura, C., Raguenes, O., Mercier, A.-Y, Braekeleer, M.D., and Ferec, M. (2000). Nramp2 analysis in hemochromatosis probands. Blood cells, Molecules, and disease, 26, 312-319
DOI
ScienceOn
|
69 |
Kishi, F. and Tabuchi, M. (1998). Human natual resistance-associated macrophage protein 2: Gene cloning and protein idcntification. Biochem. Biophysic. Res. Commun., 251, 775-783
DOI
ScienceOn
|
70 |
Knopfel, M. Georg, S., Felix, F., and Helmut, H. (2000). Characterization of an integral protein of fhe brush border membrane mediating the transport of divalent metal ions. Biophysical Journal, 79, 874-884
DOI
ScienceOn
|
71 |
Koutnikova, H., Campuzano, V., Fouiy F., Dolle, R, Cazzalini, O., and Doenig, M. (1997). Studies of human, mouse and yeast homologucs indicate an mitochondreal function for frataxin, Nature Genetics, 16, 345-351
DOI
ScienceOn
|
72 |
Govoni, G. and Gros, P. (1998). Macrophage NRAMPl and its role in resistance to microbial infections. Inflammatory Research, 47, 277-284
DOI
ScienceOn
|
73 |
Grotz, N., Fox, T, Connolly, E., Park, W., Guerinot, M.L., and Eide, D. (1998). Identification ofa family of zinc transporter genes from Arabidopsis that respond to zinc deficiency. Proceedings of the National Academy of Sciences of the USA, 95, 7220-7224
DOI
ScienceOn
|
74 |
Gruenheid, S., Canonne-Hergaux, E., Gauthier, S., Hackam, D.J., Gnnstein, and Gros, P. (1999). The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes. Journal of Experimental Medicine, 189, 831-841
DOI
ScienceOn
|
75 |
Gmenheid, S., Cellier, M., Vidal, S., and Gros, P. (1995). Identification and characterization of a second mouse Nramp gene. Genomics, 25, 514-525
DOI
ScienceOn
|
76 |
Gunshin, H., Mackeiizie, B., Bereger, U.V, Gunshin, Y., Rometo, M.E, Boron, W.E, Nussberger, S., Gollan, J.L., and Hediger, M.A. (1997). Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature, 338, 482-488
|
77 |
Hanford, J.B. (1994). Cellular iron homcostasis: a paradigm for mechanisms of posttransciiptional control of gcne exprcssion. Progivss in Liver Disease, 12, 47-62
|
78 |
Parkkila, S., Waheed. A., Britton, R.S., Bacon, B.R., Zhou, X.Y., Tomatsu, S., Fleming, R.E., and Sly, W.S. (1997). Association of the transferrin receptor in human placenta with HFE, the protein defective in hereditary hemochromatosis. Proceedings of the National Academy of Sciences of the USA, 94, 13198-13202
DOI
ScienceOn
|
79 |
Pepphriell, J.E., Edwards, J.A., and Banncrman R.M. (1982). The kinetics of iron uptake by isolatcd intestinal cells from normal mice and micc with sex-linked anemia. Blood, 60, 635-638
|
80 |
Petris, M.J., Mercer, J.E, Culvenor, J.G., Lockhart, P., Gleeson, P.A., and Camakaris, J. (1996). Ligand-reegulated transport of thc Mcnkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane: a novel mechanism of refulated trafcking. EMBO Journal, 15, 6084-6095
|
81 |
Hirsch, E.C. and Faucheux, B.A. (1998). Iron metabolism and Parkinson's discasc. Movement Disorders, 13, 39-45
DOI
ScienceOn
|
82 |
Huang, L. and Gilschier, J. (1997). A novel gene involved in zinc transport is deficient in the lethal milk mouse. NatureGenetics, 17, 292-297
|
83 |
lancu, T.C., Shiloh, H., Raja, K.B., Simpson, R.J., Petters, T.J.,Rerl, D.P, Hsu, A., aiid Good, P.F. (1995). The hypoti-aiis-fenin anemic mouse: ullrastructLiral and laser microprobe analysis observalions. Journul of Puthology, 177, 83-94
|
84 |
Ikeda-Moore, Y., Orimo, H., Hisayasu, S., and Yoshino, Y. (1995). Charactehstics of iron binding to solubillized brush border membrane of the rat intestine. J. Nutr. Sci. Vitaminol, 41,419
DOI
ScienceOn
|
85 |
Kammler, M., Schon, C., and Hantke, K. (1993). Characterization of the ferrous iron uptake system of Escherichia coli. Jounal of Bacteriology, 175, 6212-219
DOI
|
86 |
Kishi, F. (1994). Isolation aiid Cbaracterization of human Nramp cDNA. Biochem. Biophysic. Res. Commun., 204, 1074-1080
DOI
ScienceOn
|