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http://dx.doi.org/10.3807/KJOP.2017.28.5.236

Infrared Thermal Imaging for Quantification of HIFU-induced Tissue Coagulation  

Pyo, Hanjae (Department of Biomedical Engineering, Pukyong National University)
Park, Suhyun (School of Electrical and Electronics Engineering, Chung-Ang University)
Kang, Hyun Wook (Department of Biomedical Engineering, Pukyong National University)
Publication Information
Korean Journal of Optics and Photonics / v.28, no.5, 2017 , pp. 236-240 More about this Journal
Abstract
In this paper, we investigate the thermal response of skin tissue to high-intensity focused ultrasound (HIFU) by means of infrared (IR) thermal imaging. For skin tightening, a 7-MHz ultrasound transducer is used to induce irreversible tissue coagulation in porcine skin. An IR camera is employed to monitor spatiotemporal changes of the temperature in the tissue. The maximum temperature in the tissue increased linearly with applied energy, up to $90^{\circ}C$. The extent of irreversible tissue coagulation (up to 3.2 mm in width) corresponds well to the spatial distribution of the temperature during HIFU sonication. Histological analysis confirms that the temperature beyond the coagulation threshold (${\sim}65^{\circ}C$) delineates the margin of collagen denaturation in the tissue. IR thermal imaging can be a feasible method for quantifying the degree of thermal coagulation in HIFU-induced skin treatment.
Keywords
High intensity focused ultrasound; Infrared thermal imaging; Tissue coagulation;
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