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Quantitative Analysis of Eupatilin and Jaceosidin in Artemisia herba  

Ryu Su-Noh (Department of Agricultural Science, KNOU)
Kang Sam Sik (College of Pharmacy, Department of Manufacturing Pharmacy, Natural Product Research Institute, SNU)
Kim Ju Sun (College of Pharmacy, Department of Manufacturing Pharmacy, Natural Product Research Institute, SNU)
Ku Bon Il (Department of Agricultural Science, KNOU)
Publication Information
KOREAN JOURNAL OF CROP SCIENCE / v.49, no.6, 2004 , pp. 452-456 More about this Journal
Abstract
Artemisia Herb is the dry aboveground part of Artemisia asiatica (Compositae). This is listed officially in the Korean Herbal Pharmacopoeia and used mainly in stopping all kinds of bleeding, regulating menses and curing menstrual disorders as well as in alleviating pain. Eupatilin and jaceosidin were isolated from Sazabalsuk and Sajuarisuk. and identified by means of spectral methods $(UV,\;^1H\;and\;^{13}C-NMR,\;MS) $ and quantitative analysis using HPLC. Regression equations for two flavonoid component standards obtained from Artemisia asiatica were $y=76069_x\;+\;107329\;(r=0.9999^{**})$ for eupatilin, $y=76651_x\;+\;77399\;(r=0.9996^{**})$ for jaceosidin. The eupatilin content of Sazabalsuk was 240mg, jaceosidin was 10mg in 100 g dry leaves. The Sajuarisuk were 330mg, 123mg in 100g dry leaves, respectively.
Keywords
Artemisia asiatica; eupatilin; jaceosidin; extraction; isolation; quantitative analysis;
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