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http://dx.doi.org/10.14776/kjpid.2014.21.3.167

The Changes in the Outbreak of Rotavirus Gastroenteritis in Children after Introduction of Rotavirus Vaccines: A Retrospective Study at a Tertiary Hospital  

Park, Dong Kyu (Department of Pediatrics, Sanggye Paik Hospital, Inje University, College of Medicine)
Chung, Ju-Young (Department of Pediatrics, Sanggye Paik Hospital, Inje University, College of Medicine)
Publication Information
Pediatric Infection and Vaccine / v.21, no.3, 2014 , pp. 167-173 More about this Journal
Abstract
Purpose: This study aimed to examine the changes in the outbreak of acute gastroenteritis, rotavirus gastroenteritis after the introduction of the rotavirus vaccine in Korea. Methods: The current study investigated the number of inpatients in the pediatric ward of Inje University Sanggye Paik Hospital during the periods of 2005-2006 and 2011-2012. A retrospective analysis was conducted on the medical records of 2,840 patients <5 years of age who were hospitalized at Inje University Sanggye Paik Hospital in these time periods. Results: When we compared 2 separate sets of data from before (2005-2006) and after (2011-2012) vaccine introduction, there were statistically significant decreases in the number of patients who were hospitalized for acute gastroenteritis across all of the groups of patients <5 years of age except those <2 months of age. The number of patients with rotavirus gastroenteritis in all age groups declined except for children <2 months of age and those 2-5 months of age. Conclusion: These results show that after the introduction of a rotavirus vaccine in Korea, the incidence of rotavirus gastroenteritis decreased in 6-59-month-old patients hospitalized for acute gastroenteritis.
Keywords
Rotavirus; Vaccination; Gastroenteritis;
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