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http://dx.doi.org/10.6109/jkiice.2017.21.2.345

Design of 1.0V O2 and H2O2 based Potentiostat  

Kim, Jea-Duck (HiDeep)
XIAOLEI, ZHONG (Department of Semiconductor Engineering, Chungbuk National University)
Choi, Seong-Yeol (Department of Semiconductor Engineering, Chungbuk National University)
Kim, Yeong-Seuk (Department of Semiconductor Engineering, Chungbuk National University)
Abstract
In this paper, a unified potentiostat which can measure the current of both $O_2$-based and $H_2O_2$-based blood glucose sensors with low supply voltage of 1.0V has been designed and verified by simulations and measurements. Potentiostat is composed of low-voltage operational transconductance amplifier, cascode current mirrors and mode-selection circuits. It can measure currents of blood glucose chemical reactions occurred by $O_2$ or $H_2O_2$. The body of PMOS input differentional stage of the operational transconductance amplifier is forward-biased to reduce the threshold voltage for low supply voltage operation. Also, cascode current mirror is used to reduce current measurement error generated by channel length modulation effects. The proposed low-voltage potentiostat is designed and simulated using Cadence SPECTRE and fabricated in Magnachip 0.18um CMOS technology with chip size of $110{\mu}m{\times}60{\mu}m$. The measurement results show that consumption current is maximum $46{\mu}A$ at supply voltage of 1.0V. Using the persian potassium($K_3Fe(CN)_6$) equivalent to glucose, the operation of the fabricated potentiostat was confirmed.
Keywords
Potentiostat; Glucose Sensor; Operational Transconductance Amplifier; Cascode Current Mirror;
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