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http://dx.doi.org/10.4048/jbc.2018.21.e47

Current Approaches in Development of Immunotherapeutic Vaccines for Breast Cancer  

Allahverdiyev, Adil (Department of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University)
Tari, Gamze (Department of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University)
Bagirova, Melahat (Department of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University)
Abamor, Emrah Sefik (Department of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University)
Publication Information
Journal of Breast Cancer / v.21, no.4, 2018 , pp. 343-353 More about this Journal
Abstract
Cancer is the leading cause of death worldwide. In developed as well as developing countries, breast cancer is the most common cancer found among women. Currently, treatment of breast cancer consists mainly of surgery, chemotherapy, hormone therapy, and radiotherapy. In recent years, because of increased understanding of the therapeutic potential of immunotherapy in cancer prevention, cancer vaccines have gained importance. Here, we review various immunotherapeutic breast cancer vaccines including peptide-based vaccines, whole tumor cell vaccines, gene-based vaccines, and dendritic cell vaccines. We also discuss novel nanotechnology-based approaches to improving breast cancer vaccine efficiency.
Keywords
Breast neoplasms; Immunology; Immunotherapy; Vaccines;
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