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http://dx.doi.org/10.9713/kcer.2015.53.6.802

A Study on Performance Improvement of Glucose Sensor Adopting a Catalyst Using New Cross Liker  

Chung, Yongjin (Graduate School of Energy and Environment, Seoul National University of Science and Technology)
Kwon, Yongchai (Graduate School of Energy and Environment, Seoul National University of Science and Technology)
Publication Information
Korean Chemical Engineering Research / v.53, no.6, 2015 , pp. 802-807 More about this Journal
Abstract
In this study, we synthesized a new biocatalyst consisting of glucose oxidase (GOx), polyethyleneimine (PEI) and carbon nanotube (CNT) with addition of terephthalaldehyde (TPA) (TPA/GOx/PEI/CNT) for fabrication of glucose sensor that shows improved sensing ability and stability compared with that using other biocatalysts. Main bonding of the new TPA/GOx/PEI/CNT catalyst is formed by Aldol condensation reaction of functional end groups between GOx/PEI and TPA. Such formed bonding structure promotes oxidation reaction of glucose. Catalytic activity of TPA/GOx/PEI/CNT is evaluated quantitatively by electrochemical measurements. As a result of that, large sensitivity value of $41{\mu}Acm^{-2}mM^{-1}$ is gained. Regarding biosensor stability of TPA/GOx/PEI/CNT catalyst, covalent bonding formed between GOx/PEI and TPA prevents GOx molecules from becoming leaching-out and contributes improvement in biosensor stability. With estimation of the biosensor stability, it is found that the TPA/GOx/PEI/CNT catalyst keeps 94.6% of its initial activity even after three weeks.
Keywords
Glucose Oxidase; Glucose Sensor; Terephthalaldehyde; Cross Linker;
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Times Cited By KSCI : 3  (Citation Analysis)
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