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Anti-Inflammatory Action of the Fractions of Platycodi radix  

Kim, Sung-Yeun (Dept. of Food Science, Seoul Women's University)
Lee, Eun-Bang (Natural Products Research Institute, Seoul National University)
Jeong, Eun-Ja (Dept. of Food Science, Eulji University)
Publication Information
The Korean Journal of Food And Nutrition / v.22, no.4, 2009 , pp. 618-624 More about this Journal
Abstract
The extract of Platycodi radix has long been used as an anti-inflammatory traditional medicine in Korea for the treatment of bronchitis, asthma and acute respiratory disease. In this study, the anti-inflammatory actions of the methanol extract of Platycodi radix administered via oral administration were evaluated. The results revealed that the extracts exhibited potent anti-inflammatory action. Of the hexane, chloroform, ethyl acetate, butanol and water fractions, the butanol fraction had the most potent anti-inflammatory action. Additioinally the sapogenin obtained through acid hydrolysis of the butanol fraction did not show anti-inflammatory action. These findings confirm the value of Platycodi radix as a traditional Korean medicine.
Keywords
Platycodi radix; anti-inflammatory action; sapogenin; methanol extract; butanol fraction(crude saponin);
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