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http://dx.doi.org/10.7847/jfp.2018.31.2.115

Tissue concentrations of quercitrin in spotted sea bass (Lateolabrax maculatus) after extended feeding with fish mint (Houttuynia cordata) extract  

Bak, Su-Jin (East Sea Fisheries Research Institute, NIFS)
Bae, Jun Sung (Department of Aquatic Life Medicine, College of Ocean Science & Technology, Kunsan National University)
Lee, Chae Won (Department of Aquatic Life Medicine, College of Ocean Science & Technology, Kunsan National University)
Park, Kwan Ha (Department of Aquatic Life Medicine, College of Ocean Science & Technology, Kunsan National University)
Publication Information
Journal of fish pathology / v.31, no.2, 2018 , pp. 115-122 More about this Journal
Abstract
The Houttuynia cordata has been utilized for various beneficial purposes in humans mainly because of its potent antioxidant principle quercitrin present in this plant. This study examines the possibility of producing a functional sea food commodity containing active principle quercitrin by feeding H. cordata for a extended period. Spotted sea bass (Lateolabrax maculatus) were fed a diet containing H. cordata at 0.1-1.0% levels for 1 month and tissue concentrations of quercitrin were analyzed in serum, hepatopancreas and muscle. It was observed that quercitrin was found in the ranking order of hepatopancreas>muscle>serum. After a bolus administration of quercitrin (20 mg/kg, oral) to spotted sea bass and Nile tilapia (Oreochromis niloticus), idential rank order was observed after 48 hr. In contrast, the order was liver>serum>muscle in rat and mice, indicating that higher quercitrin distribution occurs to the muscle in fishes compared with in mammals tested. High residue concentration of qeurcitrin in the edible tissue can be an advantageous property in terms of functional food production. High level H. cordata extract inclusion of 1.0% seems to have detrimental effects in spotted sea bass leading to growth retardation and hepatic damage. It was concluded that incorporation of H. cordata extract into diet can be a way of producing healthy foods. However the level of active extract needs fine tuning to avoid toxicity to fishes.
Keywords
Houttuynia cordata; quercitrin concentration; spotted sea bass;
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