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http://dx.doi.org/10.12925/jkocs.2018.35.1.12

Comparison of Anti-Oxidative Activities of Perilla frutescens Extracts by Extraction Methods  

Seo, In-Yeong (Department of Clinical Laboratory Science, College of Health Sciences, Catholic University of Pusan)
Kim, Hee-Su (Department of Clinical Laboratory Science, College of Health Sciences, Catholic University of Pusan)
Jang, Kyeong-Su (Department of Clinical Laboratory Science, College of Health Sciences, Catholic University of Pusan)
Yeo, Min-Ho (Department of Clinical Laboratory Science, College of Health Sciences, Catholic University of Pusan)
Kim, Hye-Ran (Department of Clinical Laboratory Science, College of Health Sciences, Catholic University of Pusan)
Jung, Bo-Kyoung (Department of Clinical Laboratory Science, College of Health Sciences, Catholic University of Pusan)
Chang, Kyung-Soo (Department of Clinical Laboratory Science, College of Health Sciences, Catholic University of Pusan)
Publication Information
Journal of the Korean Applied Science and Technology / v.35, no.1, 2018 , pp. 12-19 More about this Journal
Abstract
Perilla frutescens (P. frutescens) is one of evergreen shrubs belonging to the Labiatae and is grown wildly in Korea. This study was carried out to evaluate the anti-oxidative effects of Perilla frutescens Extracts by Extraction Methods (water, heating and sonication). Anti-oxidative effects were measured using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and total phenol content. Cell viability and hepatoprotective effects were identified by 3-[4, 5-dimethylthiazol-2-yl]-2, 5-diphenyltetrazolium bromide (MTT) assay. Among various extracts, P. rutescens extracts by sonication showed the highest DPPH radical scavenging activity at $5000{\mu}g/mL$. Total phenolic content in P. frutescens extracts by sonication was $51.60{\pm}1.06mg\;GAE/g$ extract. However, P. frutescens extracts did not show hepatoprotective effects. This study identified anti-oxidative effects of P. frutescens extracts by sonication, and it would be necessary to perform further studies of P. frutescens extracts by sonication.
Keywords
Perilla frutescens; Extracts; Extraction methods; Anti-oxidative; Sonication;
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