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http://dx.doi.org/10.5407/JKSV.2012.10.3.025

Visualization of Rotational Flow for Chamber Size of a 2×2 Microfluidic Centrifuge  

Jeon, Hyeong Jin (부산대학교 기계공학부)
Kwon, Bong Hyun (부산대학교 기계공학부)
Kim, Dae Il (부산대학교 기계공학부)
Go, Jeung Sang (부산대학교 기계공학부)
Publication Information
Journal of the Korean Society of Visualization / v.10, no.3, 2012 , pp. 25-29 More about this Journal
Abstract
This paper introduces a new parameter to design the $2{\times}2$ microfluidic centrifuge with single flow rotation positioned at the center of microchamber. The dimensional centrifugal acceleration momentum flux which is defined as the interfacial momentum flux divided by distance from the center of the chamber explains the flow rotation and its threshold provides a reference to expect single flow rotation. Through the numerical and experimental visualization of the flow rotation, the number and position of flow rotation in the $2{\times}2$ microfluidic centrifuge were examined. At a channel width of $50{\mu}m$ and chamber width of $250{\mu}m$, single flow rotation was obtained over at a Reynolds number of 300, while at a channel width of $100{\mu}m$ and chamber width of $500{\mu}m$, single flow rotation did not appear. The numerical analysis showed that the threshold centrifugal acceleration momentum flux to obtain single flow rotation was $3500kg/m{\cdot}s^2$.
Keywords
Microfluidic centrifuge; Flow rotation; Centrifugal acceleration momentum flux; Visualization;
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1 K. K. Gunter, T. E. Gunter, A. Jarkowski, and R. N. Rosier, "A method of resuspending small vesicles from suspension by protamine aggregation and centrifugation," Anal. Biochem., vol. 120, pp. 113-124, 1982.   DOI   ScienceOn
2 J. Yang, Y. Huang, X. B. Wang, F. F. Becker, and P. R. Gascoyne, "Differential analysis of human leukocytes by dielectrophorestic field-flow-fractionation," Biophys. J., vol. 79, pp. 2680-2689, 2000.
3 E. Chmela and R. Tijssen, "A chip system for size separation of macromolecules and particles by hydrodynamic chromatography," Anal. Chem., vol. 74, pp. 3470-3475, 2002.   DOI   ScienceOn
4 B. H. Kwon, H. H. Kim, J. Cha, C. H. Ahn, T. Arakawa, S. Shoji, and J. S. Go, "Improvement of the size-selective separation of microbeads in a curved microchannel using particle focusing," Jpn. J. Appl. Phys., vol. 50, pp. 097301, 2011.   DOI
5 D. W. Inglis, J. A. Davis, R. H. Austinb, and J. C. Sturm, "Critical particle size for fractionation by deterministic lateral displacement," Lab Chip, vol. 6 pp. 655-658, 2006.   DOI   ScienceOn
6 D. H. Yoon, Y. K. Bahk, B. H. Kwon, S. S. Kim, Y-D. Kim, T. Arakawa, J. S. Go, and S. Shoji, "Improvement of filtration performance using self-turning of flow resistance," Jpn. J. Appl. Phys., vol. 50, pp. 017201, 2011.   DOI
7 J. H. Lee, J. B. Ha, Y. K. Bahk, S. H. Yoon, T. Arakawa, J. S. Ko, B. S. Shin, S. Shoji, and J. S. Go, "Microfluidic centrifuge of nano-particles using rotating flow in a microchamber," Sens. Actuators B, vol. 132 pp. 525-530, 2008.   DOI   ScienceOn