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http://dx.doi.org/10.4046/trd.2016.79.3.134

Pulmonary Tuberculosis Diagnosis: Where We Are?  

Leylabadlo, Hamed Ebrahimzadeh (Immunology Research Center, Tabriz University of Medical Sciences)
Kafil, Hossein Samadi (Drug Applied Research Center, Tabriz University of Medical Sciences)
Yousefi, Mehdi (Immunology Research Center, Tabriz University of Medical Sciences)
Aghazadeh, Mohammad (Infectious Disease and Tropical Medicine Research Center, Tabriz University of Medical Sciences)
Asgharzadeh, Mohammad (Biotechnology Research Center, Tabriz University of Medical Sciences)
Publication Information
Tuberculosis and Respiratory Diseases / v.79, no.3, 2016 , pp. 134-142 More about this Journal
Abstract
In recent years, in spite of medical advancement, tuberculosis (TB) remains a worldwide health problem. Although many laboratory methods have been developed to expedite the diagnosis of TB, delays in diagnosis remain a major problem in the clinical practice. Because of the slow growth rate of the causative agent Mycobacterium tuberculosis, isolation, identification, and drug susceptibility testing of this organism and other clinically important mycobacteria can take several weeks or longer. During the past several years, many methods have been developed for direct detection, species identification, and drug susceptibility testing of TB. A good understanding of the effectiveness and practical limitations of these methods is important to improve diagnosis. This review summarizes the currently-used advances in non-molecular and molecular diagnostics.
Keywords
Tuberculosis; Diagnosis; Tuberculosis; Multidrug-Resistant;
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