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A Case of Idiopathic Hypereosinophilic Syndrome Complicated with Pulmonary Thromboembolism and Disseminated Intravascular Coagulation  

Lee, Jong Sung (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
Lee, Hyun-Kyung (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
Lee, Sung Soon (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
Jin, Jae Yong (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
Lee, Young Min (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
Lee, Hyuk Pyo (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
Kim, Joo In (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
Ku, Bon Il (Department of Thoracic Surgery, Seoul Paik Hospital, Inje University)
Choi, Soo Jeon (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
Yum, Ho-Kee (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
Publication Information
Tuberculosis and Respiratory Diseases / v.57, no.6, 2004 , pp. 573-578 More about this Journal
Abstract
The idiopathic hypereosinophilic syndrome (HES) comprises a heterogeneous group of disorders with unknown pathogenesis characterized by persistent peripheral blood and bone marrow eosinophilia. And the eosinophil infiltrates of multiple organs in HES lead to severe organ dysfunction. The disseminated intravascular coagulation (DIC) is a rare complication of HES. We have experienced a case of HES complicated with DIC and pulmonary thromboembolism. After intravenous injection of methylprednisone, blood eosinophil count was normalized but DIC was persisted. With cortico steroid and cyclosporine therapy, the disease activity was favorably remitted.
Keywords
Idiopathic hypereosinophilic syndrome; DIC; cyclosporin; thromboembolism;
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