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http://dx.doi.org/10.3839/jabc.2016.024

Anti-oxidative and anti-proliferative activities of acetone extract of the cortex of Ulmus pumila L.  

In, Man-Jin (Department of Human Nutrition and Food Science, Chungwoon University)
Kim, Dong Chung (Department of Integrated Materials Engineering, Chungwoon University)
Publication Information
Journal of Applied Biological Chemistry / v.59, no.2, 2016 , pp. 133-136 More about this Journal
Abstract
An acetone extract in the cortex of Ulmus pumila L. was prepared to evaluate its anti-oxidative and anti-proliferative activities. The free radical scavenging activity ($EC_{50}=36.7{\mu}g/mL$) and reducing power ($EC_{50}=53.2{\mu}g/mL$) proportionally increased according to the extract concentration. The acetone extract possessed a potent anti-proliferative activity against human non-small cell lung cancer (A549, $GI_{50}=74.3{\mu}g/mL$) and human colon cancer (SNU-C4, $GI_{50}=92.8{\mu}g/mL$) cells in a dose-dependent manner, but was less effective with human normal cells (L132, human embryonic lung epithelial cell).
Keywords
Acetone extract; Anti-oxidative; Anti-proliferative; Ulmus pumila L.;
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Times Cited By KSCI : 13  (Citation Analysis)
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