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http://dx.doi.org/10.4489/MYCO.2006.34.4.230

Antitumor and Antioxidant Activities of the Extracts from Fruiting Body of Phellinus linteus  

Lee, June-Woo (Department of Food Processing and Cooking, Kyungbuk College)
Baek, Seong-Jin (Biotoxtech Co.)
Bae, Woo-Chul (Central Research Institute, Ilyang Pharm. Co. Ltd.)
Park, Jeong-Min (Central Research Institute, Ilyang Pharm. Co. Ltd.)
Kim, Yong-Seok (Central Research Institute, Ilyang Pharm. Co. Ltd.)
Publication Information
Mycobiology / v.34, no.4, 2006 , pp. 230-235 More about this Journal
Abstract
Fruiting bodies of Phellinus linteus were extracted by hot water and alkali methods. Sugar contents of PL-H (hot water extract) and PL-A (alkali water extract) were 81.1%, 37.4% and protein contents were 6.2%, 21.8%, respectively. Amino acid pattern showed that two extracts contained large amount of aspartic acid and alanine. Two extracts showed characteristic IR absorption pattern for glycosidic bond at $890\;cm^{-1}$. PL-H was divided two fractions by gel filtration chromatography and the molecular weights of each fraction were estimated to be about 10 kD and 225 kD, respectively and also PL-A was estimated 10 kD. Two extracts showed strong antitumor, immunomodulating and antioxidant activities, and were compared with commercialized glycopeptide anticancer drugs.
Keywords
Antioxidant; Antitumor; Immunostimulation; Phellinus linteus; Polysaccharide;
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