Browse > Article

The Molecular Characterization of Serogroup C Neisseria meningitidis Strains Circulating in Beijing  

Zhang, Tie-Gang (Institute of Immunization and Prevention, Beijing Center for Disease Prevention and Control)
He, Jing-Guo (Institute of Immunization and Prevention, Beijing Center for Disease Prevention and Control)
He, Xiong (Institute of Immunization and Prevention, Beijing Center for Disease Prevention and Control)
Chen, Li-Juan (Institute of Immunization and Prevention, Beijing Center for Disease Prevention and Control)
Shao, Zhu-Jun (National Institute for Communicable Disease Control and Prevention)
Sun, Mei-Ping (Institute of Immunization and Prevention, Beijing Center for Disease Prevention and Control)
Publication Information
Journal of Microbiology / v.44, no.6, 2006 , pp. 685-688 More about this Journal
Abstract
The aim of this study was to characterize the molecular features of serogroup C Neisseria meningitidis strains circulating in Beijing, China. Twenty out of 23 strains belonged to ST 4821. The causative serosubtype for meningococcal meningitis was P1.12-1,16-8. All of the strains expressed class 3 PorB protein. Among the five pulsed-field gel electrophoresis patterns observed, pattern III predominated.
Keywords
Multilocus sequence typing; Pulsed-field gel electrophoresis; Serosubtype; Serotype Serogroup C Neisseria meningitides;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
Times Cited By Web Of Science : 4  (Related Records In Web of Science)
Times Cited By SCOPUS : 5
연도 인용수 순위
1 Hu, X.J., X.W. Li, Y.D. Ji, W. Xi, and L.H. Gao 1991. Study on periodically prevalent features for epidemic cerebrospinal meningitis in China. Chinses J. Epidemiol. 12, 136-139
2 Popovic, T., G.W. Ajello, and R. Facklam. 1999. Manual for the laboratory diagnosis of meningitis caused by Neisseria meningitidis, Haemophilus influenzae and Streptococcus pneumoniae. World Health Organization, Geneva, Switzerland
3 Shao, Z.J., W. Li, J. Ren, X.F. Liang, L. Xu, B.W. Diao, M.C. Li, M.J. Lu, H.Y. Ren, Z.G. Cui, B.Q. Zhu, Z.W. Dai, L. Zhang, X. Chen, B. Kan, and J.G. Xu. 2006. Identification of a new Neisseria meningitidis serogroup C clone from Anhui province, China. Lancet 367, 419-423   DOI   ScienceOn
4 Zhang, T.G., X. He, L.J. Chen, J.G. He, M. Luo, J. Yang, Z.J. Shao, and M.P. Sun. 2006. Laboratory confirmation of a suspicious meningococcal meningitis death case. J. Microbiol. 44, 457-460   과학기술학회마을
5 Hu, X.J. 2001. Epidemiological surveillance and prophylaxis of epidemic cerebrospinal Meningitis. Chinese J. Vaccin. Immun. 7, 300-303
6 Clinical and Laboratory Standards Institute. 2005. Performance standards for antimicrobial susceptibility testing. Supplement M100-S15. Clinical and Laboratory Standards Institute, Wayne, Pa, USA
7 Morelli, G., B. Malorny, K. Muller, A. Seiler, J.F. Wang, J. del Valle, and M. Achtman. 1997. Clonal descent and microevolution of Neisseria meningitidis during 30 years of epidemic spread. Mol. Microbiol. 25, 1047-1064   DOI   ScienceOn
8 Goulding, J.N., J.V. Hookey, J. Stanley, W. Olver, K.R. Neal, D.A. Ala'Aldeen, and C. Arnold. 2000. Fluorescent amplified- fragment length polymorphism genotyping of Neisseria meningitidis identifies clones associated with invasive disease. J. Clin. Microbiol. 38, 4580-4585
9 Maiden, M.C., J.A. Bygraves, E. Feil, G. Morelli, J.E. Russell, R. Urwin, Q. Zhang, J. Zhou, K. Zurth, D.A. Caugant, I.M. Feavers, M. Achtman, and B.G. Spratt. 1998. Multilocussequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms. Proc. Natl. Acad. Sci. 95, 3140-3145
10 Sacchi, C.T., A.P. Lemos, A.M. Whitney, C.A. Solari, M.E. Brandt, C.E. Melles, C.E. Frasch, and L.W. Mayer. 1998a. Correlation between serological and sequencing analyses of the PorB outer membrane protein in the N. meningitidis serotyping system. Clin. Diagn. Lab. Immun. 5, 348-354
11 Sacchi, C.T., A.P. Lemos, M.E. Brandt, A.M. Whitney, C.E. Melles, C.A. Solari, C.E. Frasch, and L.W. Mayer. 1998b. Proposed standardization of Neisseria meningitidis PorA variable-region typing nomenclature. Clin. Diagn. Lab. Immun. 5, 845-855