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http://dx.doi.org/10.20307/nps.2021.27.4.280

Simultaneous Determination of Four Compounds from Cercidiphyllum japonicum Using HPLC-UV Analysis  

Kang, Jeongyeon (College of Pharmacy, Kangwon National University)
Jang, Hyeon Seok (College of Pharmacy, Kangwon National University)
Kim, Ju Yeol (College of Pharmacy, Kangwon National University)
Lee, Min Sung (Wild plants and Seeds Conservation Department, Baekdudaegan National Arboretum)
Bae, Young Soo (College of Forest and Environmental Sciences, Kangwon National University)
Kwon, Yongsoo (College of Pharmacy, Kangwon National University)
Yang, Heejung (College of Pharmacy, Kangwon National University)
Publication Information
Natural Product Sciences / v.27, no.4, 2021 , pp. 280-283 More about this Journal
Abstract
Cercidiphyllum japonicum is being used for the treatment of obesity and liver fibrosis in Korean local clinics. In the present study, we tried to develop an analytical methodology for the determination of the chemical markers of Cercidiphyllum japonicum. Four chemicals, maltol (1), chlorogenic acid (2), quercetin (3), and avicularin (4), were selected for method validation, and the analytical conditions were optimized and validated using high-performance liquid chromatography coupled with an ultraviolet detector (HPLC-UV). Additionally, the seasonal variations of four markers were monitored every month for six months. The contents of four chemicals markers were most detected in a sample collected in June.
Keywords
Cercidiphyllum japonicum; method validation; maltol; seasonal variation;
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