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NMR Assignment and Antimicrobial/Antioxidant Activities of 1${\beta}$-Hydroxyeuscaphic acid from the Seeds of Butyrospermum parkii  

Nyaa, Laurentine Bouquet Tankeu (Department of Chemistry, Faculty of Science, University of Dschang)
Tapondjou, Leon Azefack (Department of Chemistry, Faculty of Science, University of Dschang)
Barboni, Luciano (Dipartimento di Scienze Chimiche, Universita di Camerino)
Tamokou, Jean De Dieu (Department of Biochemistry, Faculty of Science, University of Dschang)
Kuiate, Jules Roger (Department of Biochemistry, Faculty of Science, University of Dschang)
Tane, Pierre (Department of Chemistry, Faculty of Science, University of Dschang)
Park, Hee-Juhn (Department of Pharmaceutical Engineering, Sangji University)
Publication Information
Natural Product Sciences / v.15, no.2, 2009 , pp. 76-82 More about this Journal
Abstract
Phytochemical investigation of the EtOAc and n-BuOH fractions obtained from the crude methanol extract of the seeds of Butyrospermum parkii led to the isolation of seven compounds including 1${\beta}$,2${\alpha}$,3${\alpha}$-trihydroxyurs-12-en-28-oic acid (1${\beta}$-hydroxyeuscaphic acid) which full NMR assignment is herein reported for the first time. The above extract, fractions and some of the isolated compounds were screened for antimicrobial and antioxidant activities; 1${\beta}$-hydroxyeuscaphic acid was the more potent.
Keywords
Butyrospermum parkii; Sapotaceae; Triterpenoids; Antimicrobial activity; Antioxidant activity;
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