v-Crk Induces Rac-dependent Membrane Ruffling and Cell Migration in CAS-deficient Embryonic Fibroblasts |
Sung, Bong Hwan
(Center for Distributed Sensor Network (CDSN), Department of Life Sciences, Gwangju Institute of Science and Technology)
Yeo, Myoung Gu (Center for Distributed Sensor Network (CDSN), Department of Life Sciences, Gwangju Institute of Science and Technology) Oh, Hye Jin (Center for Distributed Sensor Network (CDSN), Department of Life Sciences, Gwangju Institute of Science and Technology) Song, Woo Keun (Center for Distributed Sensor Network (CDSN), Department of Life Sciences, Gwangju Institute of Science and Technology) |
1 | Lauffenburger, D.A. and Horwitz, A.F. (1996). Cell migration: a physically integrated molecular process. Cell 84, 359-369 DOI ScienceOn |
2 | Rottner, K., Behrendt, B., Small, J.V., and Wehland, J. (1999). VASP dynamics during lamellipodia protrusion. Nat. Cell Biol. 1, 321-322 DOI ScienceOn |
3 | Tsuda, M., Makino, Y., Iwahara, T., Nishihara, H., Sawa, H., Nagashima, K., Hanafusa, H., and Tanaka, S. (2004). Crk associates with ERM proteins and promotes cell motility toward hyaluronic acid. J. Biol. Chem. 279, 46843-46850 DOI ScienceOn |
4 | Price, L.S., Leng, J., Schwartz, M.A., and Bokoch, G.M. (1998). Activation of Rac and Cdc42 by integrins mediates cell spreading. Mol. Biol. Cell 9, 1863-1871 DOI |
5 | Abassi, Y.A. and Vuori, K. (2002). Tyrosine 221 in Crk regulates adhesion-dependent membrane localization of Crk and Rac and activation of Rac signaling. EMBO J. 21, 4571-4582 DOI ScienceOn |
6 | Wu, C.-C., Su, H.-W., Lee, C.-C., Tang, M.-J., and Su, F.-C. (2005). Quantitative measurement of changes in adhesion force involving focal adhesion kinase during cell attachment, spread, and migration. Biochem. Biophys. Res. Commun. 329, 256-265 DOI ScienceOn |
7 | Matsuda, M., Mayer, B.J., Fukui, Y., and Hanafusa, H. (1990). Binding of transforming protein, P47gag-crk, to a broad range of phosphotyrosine-containing proteins. Science 248, 1537-1539 DOI |
8 | Nievers, M.G., Birge, R.B., Greulich, H., Verkleij, A.J., Hanafusa, H., and van Bergen en Henegouwen, P.M. (1997). v-Crk-induced cell transformation: changes in focal adhesion composition and signaling. J. Cell Sci. 110, 389-399 |
9 | Stam, J.C., Geerts, W. J.C., Versteeg, H.H., Verkleij, A.J., and en Henegouwen, P. (2001). The v-Crk oncogene enhances cell survival and induces activation of protein kinase B/Akt. J. Biol. Chem. 276, 25176-25183 DOI ScienceOn |
10 | Honda, H., Oda, H., Nakamoto, T., Honda, Z., Sakai, R., Suzuki, T., Saito, T., Nakamura, K., Nakao, K., Ishikawa, T., et al. (1998). Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas. Nat. Genet. 19, 361-365 DOI ScienceOn |
11 | Sugihara, K., Nakatsuji, N., Nakamura, K., Nakao, K., Hashimoto, R., Otani, H., Sakagami, H., Kondo, H., Nozawa, S., and Aiba, A. (1999). Rac 1 is required for the formation of three germ layers during gastrulation. Oncogene 17, 3427-3433 DOI |
12 | Kiyokawa, E., Hashimoto, Y., Kobayashi, S., Sugimura, H., Kurata, T., and Matsuda, M. (1998). Activation of Rac1 by a Crk SH3-binding protein, DOCK180. Genes Dev. 12, 3331-3336 DOI |
13 | Ridley, A.J. (2001). Rho GTPases and cell migration. J. Cell Sci. 114, 2713-2722 |
14 | Yamada, K. M. and Geiger, B. (1997). Molecular interactions in cell adhesion complexes. Curr. Opin. Cell Biol. 9, 76-85 DOI ScienceOn |
15 | Bear, J.E., Svitkina, T.M., Krause, M., Schafer, D.A., Loureiro, J.J., Strasser, G.A., Maly, I. V., Chaga, O.Y., Cooper, J.A., and Borisy, G.G. (2002). Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility. Cell 109, 509−521 |
16 | Hinz, B., Alt, W., Johnen, C., Herzog, V., and Kaiser, H.W. (1999). Quantifying lamella dynamics of cultured cells by SACED, a new computer-assisted motion analysis. Exp. Cell. Res. 251, 234-243 DOI ScienceOn |
17 | Lili, J., Yuchen, S., and Zhengtao, W. (2006). The Chemokine SDF-1alpha suppresses fibronectin-mediated in vitro lymphocytes adhesion. Mol. Cells 22, 308-313 |
18 | Suetsugu, S., Yamazaki, D., Kurisu, S., and Takenawa, T. (2003). Differential roles of WAVE1 and WAVE2 in dorsal and peripheral ruffle formation for fibroblast cell migration. Dev. Cell 5, 595-609 DOI ScienceOn |
19 | Yeo, M.G., Sung, B.H., Oh, H.J., Park, J.Y., Marcantonio, E.E., and Song, W.K. (2008). Focal adhesion targeting of v-Crk is essential for FAK phosphorylation and cell migration in mouse embryo fibroblasts deficient Src family kinases or p130CAS. J. Cell. Physiol. 214, 604-613 DOI ScienceOn |
20 | del Pozo, M.A., Price, L.S., Alderson, N.B., Ren, X.D., and Schwartz, M.A. (2000). Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK. EMBO J. 19, 2008-2014 DOI |
21 | Benard, V. and Bokoch, G.. (2002). Assay of CDC42, Rac, and Rho GTPase activation by affinity methods. In Methods in Enzymology, R. Iyengar and J.D. Hildebrandt, eds. (California USA: Academic Press), pp. 349-359 |
22 | Allen, W.E., Jones, G.E., Pollard, J.W., and Ridley, A.J. (1997). Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages. J. Cell Sci. 110, 707-720 |
23 | Mayer, B.J., Hamaguchi, M., and Hanafusa, H. (1988). A novel viral oncogene with structural similarity to phospholipase C. Nature 332, 272-275 DOI ScienceOn |
24 | Pinco, K.A., He, W., and Yang, J.T. (2002). Alpha4beta1 integrin regulates lamellipodia protrusion via a focal complex/focal adhesion-independent mechanism. Mol. Biol. Cell 13, 3203-3217 DOI ScienceOn |
25 | Tsuda, M., Tanaka, S., Sawa, H., Hanafusa, H., and Nagashima, K. (2002). Signaling adaptor protein v-Crk activates Rho and regulates cell motility in 3Y1 rat fibroblast cell line. Cell Growth Differ. 13, 131-139 |
26 | Craig, S.W. and Chen, H. (2003). Lamellipodia protrusion: moving interactions of vinculin and Arp2/3. Curr. Biol. 13, 236-238 DOI ScienceOn |
27 | Gu, J., Sumida, Y., Sanzen, N., and Sekiguchi, K. (2001). Laminin-10/11 and fibronectin differentially regulate integrin-dependent Rho and Rac activation via p130Cas-CrkII-DOCK180 pathway. J. Biol. Chem. 276, 27090-27097 DOI ScienceOn |
28 | Honda, H., Nakamoto, T., Sakai, R., and Hirai, H. (1999). p130Cas, an assembling molecule of actin filaments, promotes cell movement, cell migration, and cell spreading in fibroblasts. Biochem. Biophys. Res. Commun. 262, 25-30 DOI ScienceOn |
29 | Ridley, A.J., Paterson, H.F., Johnston, C.L., Diekmann, D., and Hall, A. (1992). The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 70, 401-410 DOI ScienceOn |
30 | Huttenlocher, A., Sandborg, R.R., and Horwitz, A.F. (1995). Adhesion in cell migration. Curr. Opin. Cell. Biol. 7, 697-706 DOI ScienceOn |
31 | Klemke, R.L., Leng, J., Molander, R., Brooks, P.C., Vuori, K., and Cheresh, D.A. (1998). CAS/Crk coupling serves as a "molecular switch" for induction of cell migration. J. Cell Biol. 140, 961-972 DOI ScienceOn |
32 | Kanner, S.B., Reynolds, A.B., Wang, H. C., Vines, R.R., and Parsons, J.T. (1991). The SH2 and SH3 domains of pp60src direct stable association with tyrosine phosphorylated proteins p130 and p110. EMBO J. 10, 1689-1698 |
33 | Altun-Gultekin, Z.F., Chandriani, S., Bougeret, C., Ishizaki, T., Narumiya, S., de Graaf, P., Van Bergen en Henegouwen, P., Hanafusa, H., Wagner, J.A., and Birge, R.B. (1998). Activation of Rho-dependent cell spreading and focal adhesion biogenesis by the v-Crk adaptor protein. Mol. Cell. Biol. 18, 3044-3058 DOI |
34 | Legg, J.A., Bompard, G., Dawson, J., Morris, H.L., Andrew, N., Cooper, L., Johnston, S.A., Tramountanis, G., and Machesky, L.M. (2007). N-WASP involvement in dorsal ruffle formation in mouse embryonic fibroblasts. Mol. Biol. Cell 18, 678-687 DOI ScienceOn |
35 | Bear, J.E., Loureiro, J.J., Libova, I., Faesler, R., Wehland, J., and Gertler, F.B. (2000). Negative regulation of fibroblast motility by Ena/VASP proteins. Cell 101, 717-728 DOI ScienceOn |