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http://dx.doi.org/10.1055/s-0042-1744414

Optimizing Treatment of Breast Cancer Related Lymphedema Using Combined DIEP Flap and Lymphedema Surgery  

Chang, Edward I. (Department of Plastic Surgery, University of Texas MD Anderson Cancer Center)
Publication Information
Archives of Plastic Surgery / v.49, no.2, 2022 , pp. 150-157 More about this Journal
Abstract
Patients undergoing treatment for breast cancer who undergo an axillary dissection and require adjuvant therapies such as radiation and chemotherapy are at high risk of developing lymphedema of the associated extremity. Historically, patients with lymphedema were treated with ablative procedures aimed simply to remove excess fluid and adiposity; however, the field of lymphatic surgery employing super-microsurgery techniques has witnessed tremendous advances in a relatively short period of time. Advancements in surgical instruments, microscope magnification and optics, imaging technology, and surgeon experience have ushered in a new era of hope to treat patients suffering from breast cancer-related lymphedema (BCRL). Here we aim to present the available options for patients suffering from BCRL, and the pinnacle in reconstruction and restoration for these patients.
Keywords
breast cancer lymphedema; lymphedema surgery; breast reconstruction;
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1 Patel KM, Lin CY, Cheng MH. From theory to evidence: long-term evaluation of the mechanism of action and flap integration of distal vascularized lymph node transfers. J Reconstr Microsurg 2015;31(01):26-30   DOI
2 Basta MN, Gao LL, Wu LC. Operative treatment of peripheral lymphedema: a systematic meta-analysis of the efficacy and safety of lymphovenous microsurgery and tissue transplantation. Plast Reconstr Surg 2014;133(04):905-913   DOI
3 Boccardo FM, Casabona F, Friedman D, et al. Surgical prevention of arm lymphedema after breast cancer treatment. Ann Surg Oncol 2011;18(09):2500-2505   DOI
4 Scaglioni MF, Arvanitakis M, Chen YC, Giovanoli P, Chia-Shen Yang J, Chang EI. Comprehensive review of vascularized lymph node transfers for lymphedema: outcomes and complications. Microsurgery 2018;38(02):222-229   DOI
5 Chang EI, Chu CK, Hanson SE, Selber JC, Hanasono MM, Schaverien MV. Comprehensive overview of available donor sites for vascularized lymph node transfer. Plast Reconstr Surg Glob Open 2020;8(03):e2675   DOI
6 Ozmen T, Lazaro M, Zhou Y, Vinyard A, Avisar E. Evaluation of simplified lymphatic microsurgical preventing healing approach (S-LYMPHA) for the prevention of breast cancer-related clinical lymphedema after axillary lymph node dissection. Ann Surg 2019;270(06):1156-1160   DOI
7 Johnson AR, Fleishman A, Granoff MD, et al. Evaluating the impact of immediate lymphatic reconstruction for the surgical prevention of lymphedema. Plast Reconstr Surg 2021;147(03):373e-381e   DOI
8 Saaristo AM, Niemi TS, Viitanen TP, Tervala TV, Hartiala P, Suominen EA. Microvascular breast reconstruction and lymph node transfer for postmastectomy lymphedema patients. Ann Surg 2012;255(03):468-473   DOI
9 Pons G, Abdelfattah U, Sarria J, Duch J, Masia J. Reverse lymph node mapping using indocyanine green lymphography: a step forward in minimizing donor-site morbidity in vascularized lymph node transfer. Plast Reconstr Surg 2021;147(02):207e-212e   DOI
10 Chang EI, Schaverien MV, Hanson SE, Chu CK, Hanasono MM. Evolution in surgical management of breast cancer-related lymphedema: the MD Anderson Cancer Center experience. Plast Reconstr Surg Glob Open 2020;8(03):e2674   DOI
11 Chang EI, Masia J, Smith ML. Combining autologous breast reconstruction and vascularized lymph node transfer. Semin Plast Surg 2018;32(01):36-41   DOI
12 Chang EI, Ibrahim A, Liu J, et al. Optimizing quality of life for patients with breast cancer-related lymphedema: a prospective study combining DIEP flap breast reconstruction and lymphedema surgery. Plast Reconstr Surg 2020;145(04):676e-685e   DOI
13 Schaverien MV, Chang EI. Combined deep inferior epigastric artery perforator flap with vascularized groin lymph node transplant for treatment of breast cancer-related lymphedema. Gland Surg 2021;10(01):460-468   DOI
14 Chung JH, Baek SO, Park HJ, Lee BI, Park SH, Yoon ES. Efficacy and patient satisfaction regarding lymphovenous bypass with sleevein anastomosis for extremity lymphedema. Arch Plast Surg 2019;46(01):46-56   DOI
15 Manrique OJ, Bustos SS, Kapoor T, et al. Gastroepiploic vascularized lymph node transfer for the treatment of extremity lymphedema: comparison between middle and distal inset. Gland Surg 2020;9(02):528-538   DOI
16 AlJindan FK, Lin CY, Cheng MH. Comparison of outcomes between side-to-end and end-to-end lymphovenous anastomoses for early-grade extremity lymphedema. Plast Reconstr Surg 2019;144(02):486-496   DOI
17 Ciudad P, Manrique OJ, Bustos SS, et al. Comparisons in long-term clinical outcomes among patients with upper or lower extremity lymphedema treated with diverse vascularized lymph node transfer. Microsurgery 2020;40(02):130-136   DOI
18 Feldman S, Bansil H, Ascherman J, et al. Single institution experience with lymphatic microsurgical preventive healing approach (LYMPHA) for the primary prevention of lymphedema. Ann Surg Oncol 2015;22(10):3296-3301   DOI
19 Hara H, Mihara M. Lymphaticovenous anastomosis for advanced-stage lower limb lymphedema. Microsurgery 2021;41(02):140-145   DOI
20 Nguyen AT, Chang EI, Suami H, Chang DW. An algorithmic approach to simultaneous vascularized lymph node transfer with microvascular breast reconstruction. Ann Surg Oncol 2015;22(09):2919-2924   DOI
21 Garza RM, Chang DW. Lymphovenous bypass for the treatment of lymphedema. J Surg Oncol 2018;118(05):743-749   DOI
22 Rockson SG. Lymphedema after breast cancer treatment. N Engl J Med 2018;379(20):1937-1944   DOI
23 Salgarello M, Mangialardi ML, Pino V, Gentileschi S, Visconti G. A prospective evaluation of health-related quality of life following lymphaticovenular anastomosis for upper and lower extremities lymphedema. J Reconstr Microsurg 2018;34(09):701-707   DOI
24 Engel H, Lin CY, Huang JJ, Cheng MH. Outcomes of lymphedema microsurgery for breast cancer-related lymphedema with or without microvascular breast reconstruction. Ann Surg 2018;268(06):1076-1083   DOI
25 Gould DJ, Mehrara BJ, Neligan P, Cheng MH, Patel KM. Lymph node transplantation for the treatment of lymphedema. J Surg Oncol 2018;118(05):736-742   DOI
26 Byun HK, Chang JS, Im SH, et al. Risk of lymphedema following contemporary treatment for breast cancer: an analysis of 7617 consecutive patients from a multidisciplinary perspective. Ann Surg 2021;274(01):170-178   DOI
27 Forte AJ, Boczar D, Huayllani MT, et al. Use of magnetic resonance imaging lymphangiography for preoperative planning in lymphedema surgery: a systematic review. Microsurgery 2021;41(04):384-390   DOI
28 Chang DW, Suami H, Skoracki R. A prospective analysis of 100 consecutive lymphovenous bypass cases for treatment of extremity lymphedema. Plast Reconstr Surg 2013;132(05):1305-1314   DOI
29 Cha HG, Oh TM, Cho MJ, et al. Changing the paradigm: lymphovenous anastomosis in advanced stage lower extremity lymphedema. Plast Reconstr Surg 2021;147(01):199-207   DOI
30 Armer JM, Ballman KV, McCall L, et al. Factors associated with lymphedema in women with node-positive breast cancer treated with neoadjuvant chemotherapy and axillary dissection. JAMA Surg 2019;154(09):800-809   DOI
31 Chang EI, Skoracki RJ, Chang DW. Lymphovenous anastomosis bypass surgery. Semin Plast Surg 2018;32(01):22-27   DOI
32 Cordova LZ, Hunter-Smith DJ, Rozen WM. Patient reported outcome measures (PROMs) following mastectomy with breast reconstruction or without reconstruction: a systematic review. Gland Surg 2019;8(04):441-451   DOI
33 Nelson JA, Allen RJ Jr, Polanco T, et al. Long-term patient-reported outcomes following postmastectomy breast reconstruction: an 8-year examination of 3268 patients. Ann Surg 2019;270(03):473-483   DOI
34 Ciudad P, Agko M, Perez Coca JJ, et al. Comparison of long-term clinical outcomes among different vascularized lymph node transfers: 6-year experience of a single center's approach to the treatment of lymphedema. J Surg Oncol 2017;116(06):671-682   DOI
35 Nguyen AT, Suami H, Hanasono MM, Womack VA, Wong FC, Chang EI. Long-term outcomes of the minimally invasive free vascularized omental lymphatic flap for the treatment of lymphedema. J Surg Oncol 2017;115(01):84-89   DOI
36 Boccardo F, Casabona F, De Cian F, et al. Lymphatic microsurgical preventing healing approach (LYMPHA) for primary surgical prevention of breast cancer-related lymphedema: over 4 years follow-up. Microsurgery 2014;34(06):421-424   DOI
37 Silva AK, Chang DW. Vascularized lymph node transfer and lymphovenous bypass: Novel treatment strategies for symptomatic lymphedema. J Surg Oncol 2016;113(08):932-939   DOI
38 DiSipio T, Rye S, Newman B, Hayes S. Incidence of unilateral arm lymphoedema after breast cancer: a systematic review and meta-analysis. Lancet Oncol 2013;14(06):500-515   DOI
39 Kim HO, Woo KJ, Kim BS, Kang SY, Moon BS, Yoon HJ. Lymphoscintigraphic findings as indicators of lymphaticovenous anastomosis outcome in patients with extremity lymphedema: a retrospective cohort study. Clin Nucl Med 2021;46(07):549-555   DOI
40 Yang JC, Wu SC, Lin WC, Chiang MH, Chiang PL, Hsieh CH. Super-microsurgical lymphaticovenous anastomosis as alternative treatment option for moderate-to-severe lower limb lymphedema. J Am Coll Surg 2020;230(02):216-227   DOI
41 Pereira N, Lee YH, Suh Y, et al. Cumulative experience in lymphovenous anastomosis for lymphedema treatment: the learning curve effect on the overall outcome. J Reconstr Microsurg 2018;34(09):735-741   DOI