TMEM39A and Human Diseases: A Brief Review |
Tran, Quangdon
(Department of Pharmacology and Medical Science, Metabolic Syndrome and Cell Signaling Laboratory, Research Institute for Medical Sciences, College of Medicine, Chungnam National University)
Park, Jisoo (Department of Pharmacology and Medical Science, Metabolic Syndrome and Cell Signaling Laboratory, Research Institute for Medical Sciences, College of Medicine, Chungnam National University) Lee, Hyunji (Department of Pharmacology and Medical Science, Metabolic Syndrome and Cell Signaling Laboratory, Research Institute for Medical Sciences, College of Medicine, Chungnam National University) Hong, Youngeun (Department of Pharmacology and Medical Science, Metabolic Syndrome and Cell Signaling Laboratory, Research Institute for Medical Sciences, College of Medicine, Chungnam National University) Hong, Suntaek (Laboratory of Cancer Cell Biology, Department of Biochemistry, School of Medicine, Gachon University) Park, Sungjin (Department of Pharmacology and Medical Science, Metabolic Syndrome and Cell Signaling Laboratory, Research Institute for Medical Sciences, College of Medicine, Chungnam National University) Park, Jongsun (Department of Pharmacology and Medical Science, Metabolic Syndrome and Cell Signaling Laboratory, Research Institute for Medical Sciences, College of Medicine, Chungnam National University) Kim, Seon-Hwan (Department of Neurosurgery, Institute for Cancer Research, College of Medicine, Chungnam National University) |
1 | Guttula, S.V., Allam, A. and Gumpeny, R.S. (2012) Analyzing microarray data of Alzheimer's using cluster analysis to identify the biomarker genes. Int. J. Alzheimers Dis., 2012, 649456. |
2 | Boada-Romero, E., Letek, M., Fleischer, A., Pallauf, K., Ramon-Barros, C. and Pimentel-Muinos, F.X. (2013) TMEM59 defines a novel ATG16L1-binding motif that promotes local activation of LC3. EMBO J., 32, 566-582. DOI |
3 | Dobashi, S., Katagiri, T., Hirota, E., Ashida, S., Daigo, Y., Shuin, T., Fujioka, T., Miki, T. and Nakamura, Y. (2009) Involvement of TMEM22 overexpression in the growth of renal cell carcinoma cells. Oncol. Rep., 21, 305-312. |
4 | Wrzesinski, T., Szelag, M., Cieslikowski, W.A., Ida, A., Giles, R., Zodro, E., Szumska, J., Pozniak, J., Kwias, Z., Bluyssen, H.A. and Wesoly, J. (2015) Expression of pre-selected TMEMs with predicted ER localization as potential classifiers of ccRCC tumors. BMC Cancer, 15, 518. DOI |
5 | Hayez, A., Malaisse, J., Roegiers, E., Reynier, M., Renard, C., Haftek, M., Geenen, V., Serre, G., Simon, M., de Rouvroit, C.L., Michiels, C. and Poumay, Y. (2014) High TMEM45A expression is correlated to epidermal keratinization. Exp. Dermatol., 23, 339-344. DOI |
6 | Ferrera, L., Caputo, A. and Galietta, L.J. (2010) TMEM16A protein: A new identity for -dependent channels. Physiology (Bethesda), 25, 357-363. DOI |
7 | Ishihara, K., Suzuki, J. and Nagata, S. (2016) Role of in the Stability and Function of TMEM16F and 16K. Biochemistry, 55, 3180-3188. DOI |
8 | Martin-Rendon, E., Hale, S.J., Ryan, D., Baban, D., Forde, S.P., Roubelakis, M., Sweeney, D., Moukayed, M., Harris, A.L., Davies, K. and Watt, S.M. (2007) Transcriptional profiling of human cord blood CD133+ and cultured bone marrow mesenchymal stem cells in response to hypoxia. Stem Cells, 25, 1003-1012. DOI |
9 | Abermil, N., Guillaud-Bataille, M., Burnichon, N., Venisse, A., Manivet, P., Guignat, L., Drui, D., Chupin, M., Josseaume, C., Affres, H., Plouin, P.F., Bertherat, J., Jeunemaitre, X. and Gimenez-Roqueplo, A.P. (2012) TMEM127 screening in a large cohort of patients with pheochromocytoma and/or paraganglioma. J. Clin. Endocrinol. Metab., 97, E805-E809. DOI |
10 | Dalgliesh, G.L., Furge, K., Greenman, C., Chen, L., Bignell, G., Butler, A., Davies, H., Edkins, S., Hardy, C., Latimer, C., Teague, J., Andrews, J., Barthorpe, S., Beare, D., Buck, G., Campbell, P.J., Forbes, S., Jia, M., Jones, D., Knott, H., Kok, C.Y., Lau, K.W., Leroy, C., Lin, M.L., McBride, D.J., Maddison, M., Maguire, S., McLay, K., Menzies, A., Mironenko, T., Mulderrig, L., Mudie, L., O’Meara, S., Pleasance, E., Rajasingham, A., Shepherd, R., Smith, R., Stebbings, L., Stephens, P., Tang, G., Tarpey, P.S., Turrell, K., Dykema, K.J., Khoo, S.K., Petillo, D., Wondergem, B., Anema, J., Kahnoski, R.J., Teh, B.T., Stratton, M.R. and Futreal, P.A. (2010) Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes. Nature, 463, 360-363. DOI |
11 | Singer, S.J. (1990) The structure and insertion of integral proteins in membranes. Annu. Rev. Cell Biol., 6, 247-296. DOI |
12 | International Multiple Sclerosis Genetics Consortium (IMSGC) (2010) Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci. Hum. Mol. Genet., 19, 953-962. DOI |
13 | Varade, J., Comabella, M., Ortiz, M.A., Arroyo, R., Fernandez, O., Pinto-Medel, M.J., Fedetz, M., Izquierdo, G., Lucas, M., Gomez, C.L., Rabasa, A.C., Alcina, A., Matesanz, F., Alloza, I., Antiguedad, A., Garcia-Barcina, M., Otaegui, D., Olascoaga, J., Saiz, A., Blanco, Y., Montalban, X., Vandenbroeck, K. and Urcelay, E. (2012) Replication study of 10 genes showing evidence for association with multiple sclerosis: validation of TMEM39A, IL12B and CBLB [correction of CLBL] genes. Mult. Scler., 18, 959-965. DOI |
14 | Sun, W., Qiu, G., Zou, Y., Cai, Z., Wang, P., Lin, X., Huang, J., Jiang, L., Ding, X. and Hu, G. (2015) Knockdown of TMEM45A inhibits the proliferation, migration and invasion of glioma cells. Int. J. Clin. Exp. Pathol., 8, 12657-12667. |
15 | Cuajungco, M.P., Podevin, W., Valluri, V.K., Bui, Q., Nguyen, V.H. and Taylor, K. (2012) Abnormal accumulation of human transmembrane (TMEM)-176A and 176B proteins is associated with cancer pathology. Acta Histochem., 114, 705-712. DOI |
16 | Hrasovec, S., Hauptman, N., Glavac, D., Jelenc, F. and Ravnik-Glavac, M. (2013) TMEM25 is a candidate biomarker methylated and down-regulated in colorectal cancer. Dis. Markers, 34, 93-104. DOI |
17 | Perez-Magan, E., Campos-Martin, Y., Mur, P., Fiano, C., Ribalta, T., Garcia, J.F., Rey, J.A., Rodriguez de Lope, A., Mollejo, M. and Melendez, B. (2012) Genetic alterations associated with progression and recurrence in meningiomas. J. Neuropathol. Exp. Neurol., 71, 882-893. DOI |
18 | Lessard, C.J., Adrianto, I., Ice, J.A., Wiley, G.B., Kelly, J.A., Glenn, S.B., Adler, A.J., Li, H., Rasmussen, A., Williams, A.H., Ziegler, J., Comeau, M.E., Marion, M., Wakeland, B.E., Liang, C., Ramos, P.S., Grundahl, K.M., Gallant, C.J., Alarcon- Riquelme, M.E., Alarcon, G.S., Anaya, J.M., Bae, S.C., Boackle, S.A., Brown, E.E., Chang, D.M., Cho, S.K., Criswell, L.A., Edberg, J.C., Freedman, B.I., Gilkeson, G.S., Jacob, C.O., James, J.A., Kamen, D.L., Kimberly, R.P., Kim, J.H., Martin, J., Merrill, J.T., Niewold, T.B., Park, S.Y., Petri, M.A., Pons-Estel, B.A., Ramsey-Goldman, R., Reveille, J.D., Scofield, R.H., Song, Y.W., Stevens, A.M., Tsao, B.P., Vila, L.M., Vyse, T.J., Yu, C.Y., Guthridge, J.M., Kaufman, K.M., Harley, J.B., Wakeland, E.K., Langefeld, C.D., Gaffney, P.M., Montgomery, C.G. and Moser, K.L.; BIOLUPUS Network; GENLES Network. (2012) Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study. American Journal of Human Genetics, 90, 648-660. DOI |
19 | Flamant, L., Roegiers, E., Pierre, M., Hayez, A., Sterpin, C., De Backer, O., Arnould, T., Poumay, Y. and Michiels, C. (2012) TMEM45A is essential for hypoxia-induced chemoresistance in breast and liver cancer cells. BMC Cancer, 12, 391. DOI |
20 | Lee, S., Stewart, S., Nagtegaal, I., Luo, J., Wu, Y., Colditz, G., Medina, D. and Allred, D.C. (2012) Differentially expressed genes regulating the progression of ductal carcinoma in situ to invasive breast cancer. Cancer Res., 72, 4574-4586. DOI |
21 | Guo, J., Chen, L., Luo, N., Yang, W., Qu, X. and Cheng, Z. (2015) Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells. Oncol. Rep., 33, 3124-3130. DOI |
22 | Sheng, Y.J., Xu, J.H., Wu, Y.G., Zuo, X.B., Gao, J.P., Lin, Y., Zhu, Z.W., Wen, L.L., Yang, C., Liu, L., Cheng, Y.Y., Chang, Y., Yang, L.L., Zhou, F.S., Tang, X.F., Zheng, X.D., Yin, X.Y., Tang, H.Y., Sun, L.D., Cui, Y., Yang, S. and Zhang, X.J. (2015) Association analyses confirm five susceptibility loci for systemic lupus erythematosus in the Han Chinese population. Arthritis Res. Ther., 17, 85. DOI |
23 | You, Y., Zhai, Z.F., Chen, F.R., Chen, W. and Hao, F. (2015) Autoimmune risk loci of IL12RB2, IKZF1, XKR6, TMEM39A and CSK in Chinese patients with systemic lupus erythematosus. Tissue Antigens, 85, 200-203. DOI |
24 | Huttlin, E.L., Ting, L., Bruckner, R.J., Gebreab, F., Gygi, M.P., Szpyt, J., Tam, S., Zarraga, G., Colby, G., Baltier, K., Dong, R., Guarani, V., Vaites, L.P., Ordureau, A., Rad, R., Erickson, B.K., Wuhr, M., Chick, J., Zhai, B., Kolippakkam, D., Mintseris, J., Obar, R.A., Harris, T., Artavanis-Tsakonas, S., Sowa, M.E., De Camilli, P., Paulo, J.A., Harper, J.W. and Gygi, S.P. (2015) The bioplex network: a systematic exploration of the human interactome. Cell, 162, 425-440. DOI |
25 | Jones, J., Otu, H., Spentzos, D., Kolia, S., Inan, M., Beecken, W.D., Fellbaum, C., Gu, X., Joseph, M., Pantuck, A.J., Jonas, D. and Libermann, T.A. (2005) Gene signatures of progression and metastasis in renal cell cancer. Clin. Cancer Res., 11, 5730-5739. DOI |
26 | Lips, K.S., Pfeil, U. and Kummer, W. (2002) Coexpression of alpha 9 and alpha 10 nicotinic acetylcholine receptors in rat dorsal root ganglion neurons. Neuroscience, 115, 1-5. DOI |
27 | Son, J.H., Shim, J.H., Kim, K.H., Ha, J.Y. and Han, J.Y. (2012) Neuronal autophagy and neurodegenerative diseases. Exp. Mol. Med., 44, 89-98. DOI |
28 | Beroukhim, R., Brunet, J.P., Di Napoli, A., Mertz, K.D., Seeley, A., Pires, M.M., Linhart, D., Worrell, R.A., Moch, H., Rubin, M.A., Sellers, W.R., Meyerson, M., Linehan, W.M., Kaelin, W.G., Jr. and Signoretti, S. (2009) Patterns of gene expression and copy-number alterations in von-hippel lindau disease-associated and sporadic clear cell carcinoma of the kidney. Cancer Res., 69, 4674-4681. DOI |
29 | Cifola, I., Spinelli, R., Beltrame, L., Peano, C., Fasoli, E., Ferrero, S., Bosari, S., Signorini, S., Rocco, F., Perego, R., Proserpio, V., Raimondo, F., Mocarelli, P. and Battaglia, C. (2008) Genome-wide screening of copy number alterations and LOH events in renal cell carcinomas and integration with gene expression profile. Mol. Cancer, 7, 6. DOI |
30 | Gumz, M.L., Zou, H., Kreinest, P.A., Childs, A.C., Belmonte, L.S., LeGrand, S.N., Wu, K.J., Luxon, B.A., Sinha, M., Parker, A.S., Sun, L.Z., Ahlquist, D.A., Wood, C.G. and Copland, J.A. (2007) Secreted frizzled-related protein 1 loss contributes to tumor phenotype of clear cell renal cell carcinoma. Clin. Cancer Res., 13, 4740-4749. DOI |
31 | Senft, D. and Ronai, Z.A. (2016) Regulators of mitochondrial dynamics in cancer. Curr. Opin. Cell Biol., 39, 43-52. DOI |
32 | Orvedahl, A., Sumpter, R., Jr., Xiao, G., Ng, A., Zou, Z., Tang, Y., Narimatsu, M., Gilpin, C., Sun, Q., Roth, M., Forst, C.V., Wrana, J.L., Zhang, Y.E., Luby-Phelps, K., Xavier, R.J., Xie, Y. and Levine, B. (2011) Image-based genome-wide siRNA screen identifies selective autophagy factors. Nature, 480, 113-117. DOI |
33 | Sjoblom, T., Jones, S., Wood, L.D., Parsons, D.W., Lin, J., Barber, T.D., Mandelker, D., Leary, R.J., Ptak, J., Silliman, N., Szabo, S., Buckhaults, P., Farrell, C., Meeh, P., Markowitz, S.D., Willis, J., Dawson, D., Willson, J.K., Gazdar, A.F., Hartigan, J., Wu, L., Liu, C., Parmigiani, G., Park, B.H., Bachman, K.E., Papadopoulos, N., Vogelstein, B., Kinzler, K.W. and Velculescu, V.E. (2006) The consensus coding sequences of human breast and colorectal cancers. Science, 314, 268-274. DOI |
34 | Palikaras, K., Lionaki, E. and Tavernarakis, N. (2016) Mitophagy: In sickness and in health. Mol. Cell. Oncol., 3, e1056332. DOI |
35 | Bernardini, J.P., Lazarou, M. and Dewson, G. (2016) Parkin and mitophagy in cancer. Oncogene, 36, 1315-1327. |
36 | Zhang, L., Ju, X., Cheng, Y., Guo, X. and Wen, T. (2011) Identifying Tmem59 related gene regulatory network of mouse neural stem cell from a compendium of expression profiles. BMC Syst. Biol., 5, 152. DOI |
37 | Ullrich, S., Munch, A., Neumann, S., Kremmer, E., Tatzelt, J. and Lichtenthaler, S.F. (2010) The novel membrane protein TMEM59 modulates complex glycosylation, cell surface expression, and secretion of the amyloid precursor protein. J. Biol. Chem., 285, 20664-20674. DOI |
38 | Tun, H.W., Marlow, L.A., von Roemeling, C.A., Cooper, S.J., Kreinest, P., Wu, K., Luxon, B.A., Sinha, M., Anastasiadis, P.Z. and Copland, J.A. (2010) Pathway signature and cellular differentiation in clear cell renal cell carcinoma. PLoS ONE, 5, e10696. DOI |
39 | Wang, Y., Roche, O., Yan, M.S., Finak, G., Evans, A.J., Metcalf, J.L., Hast, B.E., Hanna, S.C., Wondergem, B., Furge, K.A., Irwin, M.S., Kim, W.Y., Teh, B.T., Grinstein, S., Park, M., Marsden, P.A. and Ohh, M. (2009) Regulation of endocytosis via the oxygen-sensing pathway. Nat. Med., 15, 319-324. DOI |