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http://dx.doi.org/10.15188/kjopp.2015.12.12.29.6.443

Status of Construction of TCM Network Pharmacology Databases and Potential Application of TCMSP to Korean Traditional Medicine - mainly with Sasang-related Herbs  

Hwang, Sang Moon (Division of Longevity and Biofunctional Medicine, School of Korean Medicine, Pusan National University)
Beck, Jongmin (Division of Longevity and Biofunctional Medicine, School of Korean Medicine, Pusan National University)
Suh, Su Yeon (Division of Longevity and Biofunctional Medicine, School of Korean Medicine, Pusan National University)
Kwon, Young Kyu (Division of Longevity and Biofunctional Medicine, School of Korean Medicine, Pusan National University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.29, no.6, 2015 , pp. 443-450 More about this Journal
Abstract
The purpose of this study was is to understand how the network pharmacology databases of traditional medicine in China are established and provide suggestion for successful implementation in Traditional Korean Medicine. We searched for network-pharmacology-related TCM Databases provided on the internet, and analysed their contents. Then, we compared herbs related to Sasang with herbs of the TCM Databases. We chose 8 network-pharmacology-related TCM Databases. They shared information about compounds, herbs, formulae, drugs, targets and diseases, and provided interaction networks between these components. In comparison with herbs related to Sasang, TCMSP Database did not have information about 99 herbs in total, and 25 herbs included in major Sasang formulae. The implications and recommendations for Traditional Korean Medicine researches were discussed. Based on the results of this primary study, more related studies should be carried out in the future.
Keywords
Network pharmacology; Systems biology; TCMSP; TCM; Traditional Korean medicine; Sasang Medicine;
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