Anti-cancer Effects of Costunolide in Estrogen Receptor Positive MCF-7 Breast Cancer Cells |
Kim, Woon Ji
(Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University)
Choi, Youn Kyung (Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University) Woo, Sang Mi (Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University) Park, Nam Gyu (Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University) Jung, Hye In (Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University) Kim, Yong Gook (Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University) Shin, Yong Cheol (Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University) Ko, Seong Gyu (Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University) |
1 | Edwards, B.K., Brown, M.L., Wingo, P.A., et al. Annual report to the nation on the status of cancer, 1975-2002, featuring population-based trends in cancer treatment, J Natl Cancer Inst 97(19):1407-1427, 2005. DOI ScienceOn |
2 | Park, S., Bae, J., Nam, B.H., et al. Aetiology of cancer in Asia, Asian Pac J Cancer Prev 9(3):371-380, 2008. |
3 | Ziegler, R.G., Anderson, W.F., Gail, M.H. Increasing breast cancer incidence in China: the numbers add up, J Natl Cancer Ins 100(19):1339-1341, 2008. DOI ScienceOn |
4 | Hanahan, D., Weinberg, R.A. Hallmarks of cancer: the next generation, Cell 144(5):646-674, 2011. DOI ScienceOn |
5 | Lopez-Saez, J.F., de, la., Torre, C., et al. Cell proliferation and cancer, Histol Histopathol 13(4):1197-1214, 1998. |
6 | Nasmyth, K., Viewpoint: putting the cell cycle in order, Science 274(5293):1643-1645, 1996. DOI ScienceOn |
7 | Vermeulen, K., Van Bockstaele, D.R., Berneman, Z.N. The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer, Cell Prolif 36(3):131-149, 2003. DOI ScienceOn |
8 | Sancar, A., Lindsey-Boltz, L.A., Unsal-Kacmaz, K., et al. Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints, Annu Rev Biochem 73: 39-85, 2004. DOI ScienceOn |
9 | Ruas, M., Peters, G. The p16INK4a/CDKN2A tumor suppressor and its relatives, Biochim Biophys Acta 1378(2):F115-F177, 1998. |
10 | Sherr, C.J., Roberts, J.M. CDK inhibitors: positive and negative regulators of G1-phase progression, Genes Dev 13(12):1501-1512, 1999. DOI ScienceOn |
11 | Edinger, A.L., Thompson, C.B. Death by design: apoptosis, necrosis and autophagy, Curr Opin Cell Biol 16(6):663-669, 2004. DOI ScienceOn |
12 | Meijer, A.J., Codogno, P. Regulation and role of autophagy in mammalian cells, Int J Biochem Cell Biol 36(12):2445-2462, 2004. DOI ScienceOn |
13 | Gozuacik, D., Kimchi, A. Autophagy as a cell death and tumor suppressor mechanism, Oncogene 23(16):2891-2906, 2004. DOI ScienceOn |
14 | Rubinsztein, D.C., Gestwicki, J.E., Murphy, L.O., et al. Potential therapeutic applications of autophagy, Nat Rev Drug Discov 6(4):304-312, 2007. DOI ScienceOn |
15 | Tolkovsky, A.M. Autophagy thwarts muscle disease, Nat Med 16(11):1188-1190, 2010. DOI ScienceOn |
16 | Deretic, V. Autophagy in infection, Curr Opin Cell Biol 22(2):252-262, 2010. DOI ScienceOn |
17 | Rubinsztein, D.C., Marino, G., Kroemer, G. Autophagy and aging, Cell 146(5):682-695, 2011. DOI ScienceOn |
18 | Cao, X., Liu, B., Cao, W., et al. Autophagy inhibition enhances apigenin-induced apoptosis in human breast cancer cells, Chin J Cancer Res 25(2):212-222, 2013. |
19 | Yim, N.H., Jung, Y.P., Kim, A., et al. Oyaksungisan, a Traditional Herbal Formula, Inhibits Cell Proliferation by Induction of Autophagy via JNK Activation in Human Colon Cancer Cells, Evid Based Complement Alternat Med 2013: 231874, 2013. |
20 | Lee, M.G., Lee, K.T., Chi, S.G., et al. Costunolide induces apoptosis by ROS-mediated mitochondrial permeability transition and cytochrome C release, Biol Pharm Bull 24(3):303-306, 2001. DOI ScienceOn |
21 | De, Marino, S., Borbone, N., Zollo, F., et al. New sesquiterpene lactones from Laurus nobilis leaves as inhibitors of nitric oxide production, Planta Med 71(8):706-710, 2005. DOI ScienceOn |
22 | Mondranondra, I.O., Che, CT., Rimando, A.M., et al. Sesquiterpene lactones and other constituents from a cytotoxic extract of Michelia floribunda, Pharm Res 7(12):1269-1272, 1990. DOI |
23 | el-Feraly, F.S., Chan, Y.M., Isolation and characterization of the sesquiterpene lactones costunolide, parthenolide, costunolide diepoxide, santamarine, and reynosin from Magnolia grandiflora L, J Pharm Sci 67(3):347-350, 1978. DOI |
24 | Park, H.J., Kwon, S.H., Han, Y.N., et al. Apoptosis-Inducing costunolide and a novel acyclic monoterpene from the stem bark of Magnolia sieboldii, Arch Pharm Res 24(4):342-348, 2001. DOI |
25 | Kassuya, C.A., Cremoneze, A., Barros, L.F., et al. Antipyretic and anti-inflammatory properties of the ethanolic extract, dichloromethane fraction and costunolide from Magnolia ovata (Magnoliaceae), J Ethnopharmacol 124(3):369-376, 2009. DOI ScienceOn |
26 | Chen, H.C., Chou, C.K., Lee, S.D., et al. Active compounds from Saussurea lappa Clarks that suppress hepatitis B virus surface antigen gene expression in human hepatoma cells, Antiviral Res 27(1-2):99-109, 1995. DOI ScienceOn |
27 | Wedge, D.E., Galindo, J.C., Macias, F.A. Fungicidal activity of natural and synthetic sesquiterpene lactone analogs, Phytochemistry 53(7):747-757, 2000. DOI ScienceOn |
28 | Chen, C.N., Huang, H.H., Wu, C.L., et al. Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells, Cancer Lett 246(1-2):237-252, 2007. DOI ScienceOn |
29 | Mori, H., Kawamori, T., Tanaka, T., et al. Chemopreventive effect of costunolide, a constituent of oriental medicine, on azoxymethane-induced intestinal carcinogenesis in rats, ancer Lett 83(1-2):171-175, 1994. DOI ScienceOn |
30 | Choi, J.H., Ha, J., Park, J.H., et al. Costunolide triggers apoptosis in human leukemia U937 cells by depleting intracellular thiols, Jpn J Cancer Res 93(12):1327-1333, 2002. DOI |
31 | Hoshino, R., Chatani, Y., Yamori, T., et al. Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors, Oncogene, 18(3):813-822, 1999. DOI ScienceOn |
32 | Hsu, J.L., Pan, S.L., Ho, Y.F., et al. Costunolide induces apoptosis through nuclear calcium2+ overload and DNA damage response in human prostate cancer, J Urol 185(5):1967-1974, 2011. DOI ScienceOn |
33 | Choi, Y.K., Seo, H.S., Choi, H.S., et al. Induction of Fas-mediated extrinsic apoptosis, p21WAF1-related G2/M cell cycle arrest and ROS generation by costunolide in estrogen receptor-negative breast cancer cells, MDA-MB-231, Mol Cell Biochem 363(1-2):119-128, 2012. DOI |
34 | Jeong, S.J., Itokawa, T., Shibuya, M., et al. Costunolide, a sesquiterpene lactone from Saussurea lappa, inhibits the VEGFR KDR/Flk-1 signaling pathway, Cancer Lett 187(1-2):129-133, 2002. DOI ScienceOn |
35 | Lewis, T.S., Shapiro, P.S., Ahn, N.G. Signal transduction through MAP kinase cascades, Adv Cancer Res 74: 49-139, 1998. DOI |
36 | Paglin, S., Hollister, T., Delohery, T., et al. A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles, Cancer Res 61(2):439-444, 2001. |
37 | Kanzawa, T., Kondo, Y., Ito, H., et al. Induction of autophagic cell death in malignant glioma cells by arsenic trioxide, Cancer Res 63(9):2103-2018, 2003. |
38 | Pyo, J.O., Nah, J., Jung, Y.K. Molecules and their functions in autophagy, Exp Mol Med 44(2):73-80, 2012. DOI ScienceOn |