Browse > Article

Effect of Beverage from Inonotus Obliquus on Serum Lipid Profile Improvement  

Shin, Eon-Hwan (Department of Hotel Culinary Arts, Ulsan College)
Song, You-Jin (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University)
Han, Jong-Hyun (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University)
Park, Sung-Hye (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.19, no.2, 2005 , pp. 407-411 More about this Journal
Abstract
The purpose of this study was to investigate the possibility of Inonotus obiquus as an functional resources. We carried out to develop a beverage by using Inonotus obliquus, and we examined the effects of beverage on the reduction of serum lipid and improvement of blood parameters in rats fed high fat diet 5 weeks. Sprague-Dawley rat weigh $150\;g{\pm}15\;g$, were randomly assigned to 4 groups, basal diet only(BDG), high fat diet without beverage(FDCG), high fat diet and 10% beverage(FD10M), high fat diet and 20% beverage(FD20M). The result of this study were as follow. Hematological datas of 4 groups were same level, which were not significant. Serum GOT activity were reasonable levels in FD10M and FD20M groups compared to FDCG group. Total cholesterol, LDL-cholesterol, triglyceride in serum and atherogenic index were remarkably reduced in beverage supplemented groups as compared control group. These results imply that beverage from Inonotus obliquus could be used as possible for decrease of serum lipid concentration.
Keywords
Inonotus obliquus; high fat diet; hypolipidemic effect; beverage;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Lee, G.D., Chang, H.G., Kim, H.K. Antioxidative and nitrite- scavenging activities of edible mushrooms. Korean J Food Sci Technol 29, 432-436, 1997.
2 Kahlos, K., Hiltunen, R. Indentification of some lanostane type triterpenes from Inonotus obliquus. Acta Pharm Fenn 92, 220-224. 1983.
3 Ichimura, T., Watanave, O., Maruyama, S. Inhibition of HIV-1 protease by water soluble lignin-like substance from an edible mushroom, Fuscoporia obliqua. Biosci Biothechnol Biochem 62, 575-577.
4 Yang, M.H., Wang, C.H., Chen, H.L. Green, oolong and black tea extracts modulate lipid metabolism in hyperlipidemia rats fed high-sucrose diet. J of Nutritional Biochemistray 12, 14-20, 2001.
5 Park, P.S., Park, M.Y. Effects of Diocorea batatas and Gastrodia rhizoma on fatty acid compositions of serum, liver and brain in rats. Korean J of Life Science 11, 83-92, 2001.
6 Kim, M.H., Ka, B,J., Bae, S,J. The effects of Daucus carota L. extracts on serum lipid and antioxidative enzyme activity in ovariectomized rats. Korean J of Life Science 10, 7-13, 2002.
7 Kim, S.J., Park, C.W. , Kim, J.O., Kim, J.M, Ha, Y.L. Reduction of mouse body fats by water extract of Pleurotus ostreatus. J Food Sci Nutr 4, 130-133, 1999.
8 Kier, L. Triterpenes of Poria obliqua. J Pharm Sci 50, 471-474, 1961.
9 Kim, W.H., Bae, S.J., Kim, M.H. The effects of Sedum sarmentosum burge on serum lipid concentration in ovariectomized rats. J Korean Soc Food Sci Nutr 31, 290-294, 2002.
10 Hong, J.S., Kim, Y.H., Kim, M.K., Kim, T.Y., Kim, K.J. Studies on the lipids composition of Korean edible mushrooms. J Korean Soc Dietary Culture 5, 437-443, 1990.
11 Shivrina, A.N. Chemical characteristics of compounds extracted from Inonotus obliquus. Chem Abstr 55: 17271-17279, 1967.
12 Park, S.H., Kim, W,J., Koo, J.G., Lee, T.H., Han, J.H. Nutrition contents and health status, blood glucose response effect for NIDDH patients of Inonotus obliquus in culturing method by using unpolished rice. Korean J Oriental Physiology & Pathlogy 19(1):114-118, 2005.
13 Ludwiczak, R.S., Wrzeciono, U. Forschungen uber die chemischen bestandteil de Inonotus obliquus IV. Ergosterol Rocz Chem 34, 1701-1705, 1975.
14 Kim, M.W., Park, M.H., Kim, G.H. Effects of mushroom protein-bound polysaccharides ion blood glucose levels and energy metabolism in streptozotocin-induced diabetic rats. Korean J Nutr 30(7):743-750, 1997.
15 Loviagina, E.V., Shivrina, A.N. On steroid compound of the Chaga fungus. Biobimija 27, 794-800.
16 대한임상병리학회, 임상병리학. 고려의학, 서울, 2001.
17 Bulatov, P.K., Berezima, M.P., Jakimov, P.A. Tsaga ii ee letsebnoje primenie pri rake IV. Stadii, Leningarad. p.326, 1959.
18 Rajarathnam, S., Bang, Z. Pleurotus mushrooms as a nutritional food. In tropical mushrooms. Chang ST, Quimio TH. The Chinese University Press, Hong Kong. pp.363-380, 1982.
19 Mizuno, T., Zhuang, C., Abe, K., Okamoto, H., Kiho, T., Ukai, S., leclerc,S., Meijer, L. Antitumor and hypoglycemic activities of polysaccharides from the Sclerotia and Mycelia of Inonotus obliquus. Int J Med Mushrooms 1, 301-316, 1999.
20 Hwang, G.H., Heo, Y.R., Choi, O.J., Lee, H.J. Effects of Coriandrum sativum L. on lipid metabolism in rats with hypertriglyceridemic diet. Nutritional Science 4, 13-19, 2001.
21 Han. H.K., Lim, S.J. Effect of fractions from methanol extract of Commelina ommuris on blood glucose level and energy metabolism in streptozotocin-induced diabetic rats. Korean J Soc Food Sci 14, 577-583, 1998.
22 Choi, H,J., Park, J.H., Han, H.S., Son, J.H., Son, G.M., Bae, J.H., Choi, C Effect of polyphenol compound from Korean pear on lipid metabolism. J Korean Soc Food Sci Nutr 33, 299-304, 2004.
23 Cho, Y.J., Kim, H.A., Bang, M.A., Kim, E.H. Effects of dietary mushroom on blood glucose levels, lipid concentration and glutathione enzymes in streptozotocininduced diabetic rats. Korean J Nutrition 35(2):183-191, 2002.
24 Andrea, C , Milena, N., Elena, C , Lina, P. Novel lipid-lowering properties of Vaccinium myrtillusi leaves, a traditional antidiabetic treatment, in several models of rats dyslipidaemia : A comparison with ciprofibrate. Thrombosis research 84, 311-322, 1996.
25 Kang, J.O., Kim, K.S. The effect of dry edible leaves feeding on serum lipids of hypercholesterolemic rats. J Korean Soc Food Sci Nutr 24, 502-509, 1995.
26 Hong, J.S., Kim, Y.H., Lee, K.R., Kim, M.K., Cho, C l., Park, K.H., Choi, Y.H., Lee, J.B. Composition of organic acid, fatty acid in Pleurotus ostreatus, Lentinus edodes and Agaricus bisporus. Korean J Food Sci Technol 20, 100-106, 1988.