Influence of Geijibokryunghwan on Platelet Aggregation, Cyclic AMP, Cyclic GMP, TXA2, Mobilization, Tyrosine Phosphorylation of PLC-2 and IP3 in Activated Platelets |
Kim Han Geu
(Department of Diagnostics, College of Oriental Medicine, Dongguk University)
Kim Jong Gu (Department of Diagnostics, College of Oriental Medicine, Dongguk University) Kim Seog Ha (Department of Diagnostics, College of Oriental Medicine, Dongguk University) Sa Eun-Ho (Department of Diagnostics, College of Oriental Medicine, Dongguk University) Kim Jae-Woo (Department of Diagnostics, College of Oriental Medicine, Dongguk University) Moon Jin Young (Department of AM-Pointology, College of Oriental Medicine, Dongguk University) Park Sun Dong (Department of Prescription, College of Oriental Medicine, Dongguk University) Choi Dall Yeong (Department of Pathology, College of Oriental Medicine, Dongguk University) Kim Cherl Ho (Department of Biochemistry, College of Oriental Medicine, Dongguk University) Park Won Hwan (Department of Diagnostics, College of Oriental Medicine, Dongguk University) |
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The antiplatelet activity of Geiji-Bokryung-Hwan, Korean traditional formulation, is mediated through inhibition of phospholipase C and inhibition of TxB(2) synthetase activity
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Inhibition of platelet aggregation and reduced formation of thromboxane and lipoxygenase products in platelets by oil of cloves
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Altered arachidonic acid metabolism in platelets inhibited by onion or garlic extracts
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Selective suppression of platelet thromboxane formation with sparing of vascular prostacyclin synthesis by aqueous extract of garlic in rabbits
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Intracellular levels of cyclic AMP and cyclic GMP differentially modify platelet aggregate size in human platelets activated with epinephrine or ADP
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Cyclic nucleotides and intracellular-calcium homeostasis in human platelets
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Role of Ca2+-ATPases in regulation of cellular Ca2+ signalling, as studied with the selective microsomal Ca2+-ATPase inhibitor, thapsigargin
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Thapsigargin, a tumor promoter, discharges intracellular Ca<TEX>$^{2+}$</TEX> stores by specific inhibition of the endoplasmic reticulum Ca<TEX>$^{2+}$</TEX>-ATPase
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Tyrosine phosphorylation of the Fc receptor -chain in collagen-stimulated platelets
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A collagen-related peptide regulates phospholipase C2 via phosphatidylinositol 3-kinase in human platelets
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2APB, 2-aminoethoxydiphenyl borate, a membrane-penetrable modulator of Ins(1,4,5)P3-induced Ca<TEX>$^{2+}$</TEX> release.
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Attenuation of intracellular Ca<TEX>$^{2+}$</TEX> and secretory responses by Ins(1,4,5)P3-induced Ca<TEX>$^{2+}$</TEX> release modulator, 2APB, in rat pancreatic acinar cells
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An Experimental Study on the Effect of Geijibokryunghwan, Dangguijakyaksan and Each Constituent Herb on Inhibition of Platelet Aggregation
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Effects of the Geijibokryunghwan on carrageenan- induced inflammation and COX-2 in hepatoma cells
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Effect of the Geijibokryunghwan on human hepatocarcinoma cells
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Endogenous cleavage of phospholipase C-3 by agonist-induced activation of calpain in human platelets
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Syk and Fyn are required by mouse megakaryocytes for the rise in intracellular calcium induced by a collagen-related peptide
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A Chinese hamster fibroblast mutant defective in thrombin-induced signaling has a low level of phospholipase C 1
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Xestospongins, Potent membrane permeable blockers of the inositol 1,4,5-trisphosphate receptor
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Xestospongin C-sensitive Ca<TEX>$^{2+}$</TEX> store is required for cAMP-induced Ca<TEX>$^{2+}$</TEX> influx and cAMP oscillations in Dictyostelium
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Inhibition of platelet aggregation and thromboxane synthesis by onion and garlic
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A water-extract of the Korean traditional formulation Geiji-Bokryung-Hwan reduces atherosclerosis and hypercholesteremia in cholesterol-fed rabbits
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Effect of the Geijibokryunghwan water extracts on stimulus-induced superoxide generation and tyrosyl phosphorylation in human neutrophils
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An Experimental stydy on the Effect of Geijibokryunghwan, Dangguijakyaksan and Each Constituent Herb on Inhibition of Platelet Aggregation
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