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Effects of Gamichihyo-san and Gamiijung-tang on Airway Mucus Secretion  

Ryu In Sun (Department of Internal Medicine, College of Oriental Medicine, Daejeon University)
Kim Yoon Sik (Department of Internal Medicine, College of Oriental Medicine, Daejeon University)
Seol In Chan (Department of Internal Medicine, College of Oriental Medicine, Daejeon University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.18, no.6, 2004 , pp. 1746-1751 More about this Journal
Abstract
This study was done to investigate the effects of Gamichihyo-san and Gamiijung-tang on airway mucus secretion. After administer Gamichihyo-san(GCHS) and Gamiijung-tang(GIJT) extract to Golden Syrian Hamster for 8-10 weeks, we examined mucin release from cultured hamster tracheal surface epithelial(HTSE) cells. Following results were obtained; GCHG significantly stimulated mucin release from cultured HTSE cells, with minute cytotoxicity GIJT did not affect mucin release and have no cytotoxicity; GCHG and GIJT did not affect contractility of isolated tracheal smooth muscle. These results suggest that Gamichihyo-san might be usefully applied for airway mucus secretion.
Keywords
goblet cell; mucos; Gamichihyo-san(GCHS); Gamiijung-tang(GIJT);
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