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Effect of Gamidojeok-san on Hypertension  

Sin Hwang Su (Department of Internal Medicine, College of Oriental Medicine, Daejeon University)
Oh Young Seon (Hyehwa Hospital, Taejeon University)
Kim Yoon Sik (Department of Internal Medicine, College of Oriental Medicine, Daejeon University)
Seol In Chan (Department of Internal Medicine, College of Oriental Medicine, Daejeon University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.18, no.6, 2004 , pp. 1710-1713 More about this Journal
Abstract
This study was Investigated to prove the effect of Gamidojeok-san (Jiaweidaochi-san) on the hypertension. After administer Gamidojeok-san (Jiaweidaochi-san) extract to SHR(Spontaneous Hypertensive Rat) for 5 weeks, we examined changes of blood pressure, pulse rate, aldosterone and catecholamine in serum. Results : Following results were obtained; Gamidojeok-san(Jiaweidaochi-san) showed significant antihypertensive effect. Gamidojeok-san(Jiaweidaochi-san) decreased pulse rate but insignificant. Gamidojeok-san(Jiaweidaochi-san) showed a significant decrease in the aldosterone. Gamidojeok-san(Jiaweidaochi-san) was ineffective on the dopamine. Gamidojeok-san(Jiaweidaochi-san) decreased the norepinephrine but insignificant. Gamidojeok-san(Jiaweidaochi-san) showed a significant decrease in the epinephrine. These results indicate that Gamidojeok-san(Jiaweidaochi-san) can be used in hypertension. Further study will be needed about the functional mechanism and etc..
Keywords
Gamidojeok-san(Jiaweidaochi-san); hypertension; aldosterone; dopamine; norepinephrine; epinephrine;
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