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Treatment Outcomes after Endoscopic Submucosal Dissection of Large Superficial Rectosigmoid Colon Tumors  

Koh, Jin-Sung (Division of Gastroenterology, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine)
Park, Jong-Jae (Division of Gastroenterology, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine)
Jung, Won-Ho (Division of Gastroenterology, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine)
Lee, Joon-Young (Division of Gastroenterology, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine)
Lim, Sang-Ah (Division of Gastroenterology, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine)
Kwon, Min-Jung (Division of Gastroenterology, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine)
Noh, Hye-Jin (Division of Gastroenterology, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine)
Joo, Moon-Kyung (Division of Gastroenterology, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine)
Lee, Beom-Jae (Division of Gastroenterology, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine)
Kim, Ji-Hoon (Division of Gastroenterology, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine)
Yeon, Jong-Eun (Division of Gastroenterology, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine)
Kim, Jae-Seon (Division of Gastroenterology, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine)
Byun, Kwan-Soo (Division of Gastroenterology, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine)
Bak, Young-Tae (Division of Gastroenterology, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine)
Publication Information
Clinical Endoscopy / v.42, no.4, 2011 , pp. 222-227 More about this Journal
Abstract
Background/Aims: Endoscopic submucosal dissection (ESD) of a colorectal tumor is technically difficult. This study aimed to analyze the clinical outcomes of superficial large rectosigmoid tumors after ESD. Methods: Medical records of 15 patients with large rectosigmoid tumors (more than 30mm), in which ESD performed, were reviewed retrospectively. Results: The mean tumor size was $42.5{\pm}14.3mm$ (range, 30~78 mm). A histological examination revealed a well-differentiated adenocarcinoma in five cases (33.3%), adenoma with high-grade dysplasia in six cases (40%), and low-grade dysplasia in four cases (26.7%). The mean procedural time was $90.5{\pm}60.7$ min (range, 22~246 min). The en bloc resection rate was 86.7%, and the complete resection rate 100%. The lateral resection margin was positive in four cases (26.6%), but no cases with a positive vertical margin were observed. Bleeding occurred in three cases (20%), and all were treated successfully using endoscopic measures. Perforations occurred in three cases (20%); two cases were treated by clipping and the other by a laparotomy. Conclusions: ESD is a treatment option for superficial large rectosigmoid tumors. Further studies with larger cases and a longer term follow-up are needed to establish the efficacy and safety of ESD for colorectal tumors.
Keywords
Endoscopic submucosal dissection; Large superficial tumor; Rectosigmoid colon; Outcomes;
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Times Cited By KSCI : 4  (Citation Analysis)
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