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http://dx.doi.org/10.3345/kjp.2010.53.4.603

A case of paraneoplastic limbic encephalitis due to ovarian mature teratoma  

Kim, Seong-Heon (Department of Pediatrics, Pusan National University Hospital Pusan National University College of Medicine)
Kim, Hye-Young (Department of Pediatrics, Pusan National University Hospital Pusan National University College of Medicine)
Im, Young-Tak (Department of Pediatrics, Pusan National University Hospital Pusan National University College of Medicine)
Nam, Sang-Ook (Department of Pediatrics, Pusan National University Hospital Pusan National University College of Medicine)
Kim, Young-Mi (Department of Pediatrics, Pusan National University Hospital Pusan National University College of Medicine)
Publication Information
Clinical and Experimental Pediatrics / v.53, no.4, 2010 , pp. 603-606 More about this Journal
Abstract
Paraneoplastic limbic encephalitis, a remote effect of cancer without nervous system metastasis, is rare, especially in childhood. Here, we report a case of paraneoplastic limbic encephalitis associated with an ovarian mature teratoma in an adolescent girl. The 15-year-old girl developed neuropsychiatric symptoms, memory loss, seizures, and unconsciousness. Cerebrospinal fluid analysis and brain magnetic resonance imaging (MRI) findings were normal, while single photon emission computed tomography imaging showed hypoperfusion in both temporal lobes. Ultrasound and MRI of the abdomen revealed a left ovarian cystic mass. The patient experienced a significant recovery of cognitive function after surgical resection of the tumor, which was pathologically identified as a mature ovarian teratoma, and treatment with intravenous immunoglobulin.
Keywords
Paraneoplastic limbic encephalitis; Teratoma; Adolescent;
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