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http://dx.doi.org/10.3904/kjim.2016.227

Fundamental role of dendritic cells in inducing Th2 responses  

Kim, Byoungjae (Department of Otorhinolaryngology-Head & Neck Surgery, Korea University College of Medicine)
Kim, Tae Hoon (Department of Otorhinolaryngology-Head & Neck Surgery, Korea University College of Medicine)
Publication Information
The Korean journal of internal medicine / v.33, no.3, 2018 , pp. 483-489 More about this Journal
Abstract
A mysterious puzzle in immunology is how the immune system decides what types of immune response to initiate against various stimuli. Although much is known about control of T helper 1 (Th1) and Th17 responses, the mechanisms that initiate Th2 responses remain obscure. Antigen-presenting cells, particularly dendritic cells (DCs), are mandatory for the induction of a Th cell response. Numerous studies have documented the organizing role of DCs in this process. The present review summarizes the fundamental roles of DCs in inducing Th2 responses.
Keywords
Antigen-presenting cells; Dendritic cells; Th2 responses;
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