1 |
Halliwell B, Gutteridge JM. Free Radicals in Biology and Medicine. 4th ed. Oxford: Clarendon Press, 2007.
|
2 |
Sugamura K, Keaney JF Jr. Reactive oxygen species in cardiovascular disease. Free Radic Biol Med 2011;51:978-992.
DOI
|
3 |
Niki E. Assessment of antioxidant capacity in vitro and in vivo. Free Radic Biol Med 2010;49:503-515.
DOI
|
4 |
Palmer S. Diet, nutrition, and cancer. Prog Food Nutr Sci 1985;9:283-341.
|
5 |
Gey KF, Brubacher GB, Stahelin HB. Plasma levels of antioxidant vitamins in relation to ischemic heart disease and cancer. Am J Clin Nutr 1987;45(5 Suppl):1368-1377.
DOI
|
6 |
Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. JAMA 2007;297:842-857.
DOI
|
7 |
Traber MG, Frei B, Beckman JS. Vitamin E revisited: do new data validate benefits for chronic disease prevention? Curr Opin Lipidol 2008;19:30-38.
|
8 |
Niki E. Do free radicals play causal role in atherosclerosis? Low density lipoprotein oxidation and vitamin E revisited. J Clin Biochem Nutr 2011;48:3-7.
|
9 |
Niki E. Lipid peroxidation: physiological levels and dual biological effects. Free Radic Biol Med 2009;47:469-484.
DOI
|
10 |
Niki E. Biomarkers of lipid peroxidation in clinical material. Biochim Biophys Acta 2014;1840:809-817.
DOI
|
11 |
Yin H, Xu L, Porter NA. Free radical lipid peroxidation: mechanisms and analysis. Chem Rev 2011;111:5944-5972.
DOI
|
12 |
Cheeseman KH, Albano EF, Tomasi A, Slater TF. Biochemical studies on the metabolic activation of halogenated alkanes. Environ Health Perspect 1985;64:85-101.
DOI
|
13 |
Recknagel RO. Carbon tetrachloride hepatotoxicity. Pharmacol Rev 1967;19:145-208.
|
14 |
Smathers RL, Galligan JJ, Stewart BJ, Petersen DR. Overview of lipid peroxidation products and hepatic protein modification in alcoholic liver disease. Chem Biol Interact 2011;192:107-112.
DOI
|
15 |
Sid B, Verrax J, Calderon PB. Role of oxidative stress in the pathogenesis of alcohol-induced liver disease. Free Radic Res 2013;47:894-904.
DOI
|
16 |
Adachi J, Asano M, Ueno Y, Naito T. Identification of 7-hydroperoxycholesterol in human liver by liquid chromatography-mass spectrometry. Alcohol Clin Exp Res 2000;24(4 Suppl):21S-25S.
|
17 |
Aleynik SI, Leo MA, Aleynik MK, Lieber CS. Increased circulating products of lipid peroxidation in patients with alcoholic liver disease. Alcohol Clin Exp Res 1998;22:192-196.
DOI
|
18 |
Wierzbicki AS, Oben J. Nonalcoholic fatty liver disease and lipids. Curr Opin Lipidol 2012;23:345-352.
DOI
|
19 |
Sumida Y, Niki E, Naito Y, Yoshikawa T. Involvement of free radicals and oxidative stress in NAFLD/NASH. Free Radic Res 2013;47:869-880.
DOI
|
20 |
Feldstein AE, Lopez R, Tamimi TA, et al. Mass spectrometric profiling of oxidized lipid products in human nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. J Lipid Res 2010;51:3046-3054.
DOI
|
21 |
Terao K, Niki E. Damage to biological tissues induced by radical initiator 2,2'-azobis(2-amidinopropane) dihydrochloride and its inhibition by chain-breaking antioxidants. J Free Radic Biol Med 1986;2:193-201.
DOI
|
22 |
Morita M, Ishida N, Uchiyama K, et al. Fatty liver induced by free radicals and lipid peroxidation. Free Radic Res 2012;46:758-765.
DOI
|
23 |
Yoshida Y, Hayakawa M, Cynshi O, Jishage K, Niki E. Acceleration of lipid peroxidation in alpha-tocopherol transfer protein-knockout mice following the consumption of drinking water containing a radical initiator. J Oleo Sci 2008;57:577-583.
DOI
|
24 |
Sanyal AJ, Chalasani N, Kowdley KV, et al. Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. N Engl J Med 2010;362:1675-1685.
DOI
|
25 |
Cheng J, Joyce A, Yates K, Aouizerat B, Sanyal AJ. Metabolomic profiling to identify predictors of response to vitamin E for non-alcoholic steatohepatitis (NASH). PLoS One 2012;7:e44106.
DOI
|
26 |
Sumida Y, Naito Y, Tanaka S, et al. Long-term (>=2 yr) efficacy of vitamin E for non-alcoholic steatohepatitis. Hepatogastroenterology 2013;60:1445-1450.
|
27 |
Steinberg D. The LDL modification hypothesis of atherogenesis: an update. J Lipid Res 2009;50 Suppl:S376-S381.
DOI
|
28 |
Barter PJ, Nicholls S, Rye KA, Anantharamaiah GM, Navab M, Fogelman AM. Antiinflammatory properties of HDL. Circ Res 2004;95:764-772.
DOI
|
29 |
Colas R, Pruneta-Deloche V, Guichardant M, et al. Increased lipid peroxidation in LDL from type-2 diabetic patients. Lipids 2010;45:723-731.
DOI
|
30 |
Noguchi N, Numano R, Kaneda H, Niki E. Oxidation of lipids in low density lipoprotein particles. Free Radic Res 1998;29:43-52.
DOI
|
31 |
Garcia-Cruset S, Carpenter KL, Guardiola F, Stein BK, Mitchinson MJ. Oxysterol profiles of normal human arteries, fatty streaks and advanced lesions. Free Radic Res 2001;35:31-41.
DOI
|
32 |
Niu X, Zammit V, Upston JM, Dean RT, Stocker R. Coexistence of oxidized lipids and alpha-tocopherol in all lipoprotein density fractions isolated from advanced human atherosclerotic plaques. Arterioscler Thromb Vasc Biol 1999;19:1708-1718.
DOI
|
33 |
Suarna C, Dean RT, May J, Stocker R. Human atherosclerotic plaque contains both oxidized lipids and relatively large amounts of alpha-tocopherol and ascorbate. Arterioscler Thromb Vasc Biol 1995;15:1616-1624.
DOI
|
34 |
Kuhn H, Romisch I, Belkner J. The role of lipoxygenase-isoforms in atherogenesis. Mol Nutr Food Res 2005;49:1014-1029.
DOI
|
35 |
Malle E, Marsche G, Arnhold J, Davies MJ. Modification of low-density lipoprotein by myeloperoxidase-derived oxidants and reagent hypochlorous acid. Biochim Biophys Acta 2006;1761:392-415.
DOI
|
36 |
Wagner JR, Motchnik PA, Stocker R, Sies H, Ames BN. The oxidation of blood plasma and low density lipoprotein components by chemically generated singlet oxygen. J Biol Chem 1993;268:18502-18506.
|
37 |
Traber MG, Atkinson J. Vitamin E, antioxidant and nothing more. Free Radic Biol Med 2007;43:4-15.
DOI
|
38 |
Sato K, Niki E, Shimasaki H. Free radical-mediated chain oxidation of low density lipoprotein and its synergistic inhibition by vitamin E and vitamin C. Arch Biochem Biophys 1990;279:402-405.
DOI
|
39 |
Bowry VW, Ingold KU, Stocker R. Vitamin E in human low-density lipoprotein: when and how this antioxidant becomes a pro-oxidant. Biochem J 1992;288(Pt 2):341-344.
DOI
|
40 |
Niki E, Noguchi N. Dynamics of antioxidant action of vitamin E. Acc Chem Res 2004;37:45-51.
DOI
|
41 |
Corongiu FP, Poli G, Dianzani MU, Cheeseman KH, Slater TF. Lipid peroxidation and molecular damage to polyunsaturated fatty acids in rat liver: recognition of two classes of hydroperoxides formed under conditions in vivo. Chem Biol Interact 1986;59:147-155.
DOI
|
42 |
Niki E. Tocopherylquinone and tocopherylhydroquinone. Redox Rep 2007;12:204-210.
DOI
|
43 |
Jishage K, Arita M, Igarashi K, et al. Alpha-tocopherol transfer protein is important for the normal development of placental labyrinthine trophoblasts in mice. J Biol Chem 2001;276:1669-1672.
DOI
|
44 |
Niki E. Role of vitamin E as a lipid-soluble peroxyl radical scavenger: in vitro and in vivo evidence. Free Radic Biol Med 2014;66:3-12.
DOI
|
45 |
Murer SB, Aeberli I, Braegger CP, et al. Antioxidant supplements reduced oxidative stress and stabilized liver function tests but did not reduce inflammation in a randomized controlled trial in obese children and adolescents. J Nutr 2014;144:193-201.
DOI
|
46 |
Miller ER 3rd, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E. Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Ann Intern Med 2005;142:37-46.
DOI
|
47 |
Li L, Chen CY, Aldini G, et al. Supplementation with lutein or lutein plus green tea extracts does not change oxidative stress in adequately nourished older adults. J Nutr Biochem 2010;21:544-549.
DOI
|
48 |
Rimm EB, Stampfer MJ, Ascherio A, Giovannucci E, Colditz GA, Willett WC. Vitamin E consumption and the risk of coronary heart disease in men. N Engl J Med 1993;328:1450-1456.
DOI
|
49 |
Stampfer MJ, Hennekens CH, Manson JE, Colditz GA, Rosner B, Willett WC. Vitamin E consumption and the risk of coronary disease in women. N Engl J Med 1993;328:1444-1449.
DOI
|
50 |
Dotan Y, Pinchuk I, Lichtenberg D, Leshno M. Decision analysis supports the paradigm that indiscriminate supplementation of vitamin E does more harm than good. Arterioscler Thromb Vasc Biol 2009;29:1304-1309.
DOI
|
51 |
Myung SK, Ju W, Cho B, et al. Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials. BMJ 2013;346:f10.
DOI
|
52 |
Vardi M, Levy NS, Levy AP. Vitamin E in the prevention of cardiovascular disease: the importance of proper patient selection. J Lipid Res 2013;54:2307-2314.
DOI
|
53 |
Asleh R, Blum S, Kalet-Litman S, et al. Correction of HDL dysfunction in individuals with diabetes and the haptoglobin 2-2 genotype. Diabetes 2008;57:2794-2800.
DOI
|
54 |
Niki E. Do antioxidants impair signaling by reactive oxygen species and lipid oxidation products? FEBS Lett 2012;586:3767-3770.
DOI
|
55 |
Forman HJ, Maiorino M, Ursini F. Signaling functions of reactive oxygen species. Biochemistry 2010;49:835-842.
DOI
|
56 |
Itoh K, Mimura J, Yamamoto M. Discovery of the negative regulator of Nrf2, Keap1: a historical overview. Antioxid Redox Signal 2010;13:1665-1678.
DOI
|
57 |
Finley JW, Kong AN, Hintze KJ, Jeffery EH, Ji LL, Lei XG. Antioxidants in foods: state of the science important to the food industry. J Agric Food Chem 2011;59:6837-6846.
DOI
|
58 |
Davies MJ. Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention. J Clin Biochem Nutr 2011;48:8-19.
|
59 |
Curtis AJ, Bullen M, Piccenna L, McNeil JJ. Vitamin E supplementation and mortality in healthy people: a meta- analysis of randomised controlled trials. Cardiovasc Drugs Ther 2014;28:563-573.
DOI
|
60 |
Jiang S, Pan Z, Li H, Li F, Song Y, Qiu Y. Meta-analysis: low-dose intake of vitamin E combined with other vitamins or minerals may decrease all-cause mortality. J Nutr Sci Vitaminol (Tokyo) 2014;60:194-205.
DOI
|
61 |
Abner EL, Schmitt FA, Mendiondo MS, Marcum JL, Kryscio RJ. Vitamin E and all-cause mortality: a meta-analysis. Curr Aging Sci 2011;4:158-170.
DOI
|
62 |
Traber MG. Mechanisms for the prevention of vitamin E excess. J Lipid Res 2013;54:2295-2306.
DOI
|
63 |
Upston JM, Terentis AC, Stocker R. Tocopherol-mediated peroxidation of lipoproteins: implications for vitamin E as a potential antiatherogenic supplement. FASEB J 1999;13:977-994.
DOI
|