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http://dx.doi.org/10.3904/kjim.2007.22.2.113

Castleman Disease Presenting with Jaundice: A Case with the Multicentric Hyaline Vascular Variant  

Park, Jun-Bean (Department of Internal Medicine, Seoul National University College of Medicine)
Hwang, Jin-Hyeok (Department of Internal Medicine, Seoul National University College of Medicine)
Kim, Hae-Ryoung (Department of Pathology, Seoul National University Bundang Hospital)
Choe, Hyung-Sim (Department of Radiology, Seoul National University Bundang Hospital)
Kim, Yu-Kyeong (Department of Nuclear Medicine, Seoul National University Bundang Hospital)
Kim, Hong-Bin (Department of Internal Medicine, Seoul National University College of Medicine)
Bang, Soo-Mee (Departments of Internal Medicine, Seoul National University Bundang Hospital)
Publication Information
The Korean journal of internal medicine / v.22, no.2, 2007 , pp. 113-117 More about this Journal
Abstract
Castleman disease (CD) is a rare lymphoproliferative disorder of unknown etiology with different clinical manifestations. A previous healthy 50 year-old man was hospitalized for right upper quadrant (RUQ) abdominal pain. He had jaundice and a 1 cm-sized lymph node in the right supraclavicular area. Pancreas and biliary computed tomography (CT) showed masses at the right renal hilum and peripancreatic areas. Positron emission tomography (PET) showed widespread systemic lymphadenopathy. Excisional biopsy of the right supraclavicular node revealed a hyaline vascular variant of CD. Corticosteroid therapy was started and the extent of disease decreased. We here report a case of multicentric CD, the hyaline vascular variant, presenting with jaundice, diagnosed by excisional biopsy and successfully treated with corticosteroids.
Keywords
Lymphoproliferative Disorder; Jaundice; Obstructive; Castleman Disease;
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