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http://dx.doi.org/10.5653/cerm.2014.41.1.9

Comparison between intracytoplasmic sperm injection and intracytoplasmic morphologically selected sperm injection in oligo-astheno-teratozoospermia patients  

Kim, Hyung Jun (Maria Fertility Hospital)
Yoon, Hye Jin (Maria Fertility Hospital)
Jang, Jung Mi (Maria Fertility Hospital)
Oh, Hwa Soon (Maria Fertility Hospital)
Lee, Yong Jun (Maria Fertility Hospital)
Lee, Won Don (Maria Fertility Hospital)
Yoon, San Hyun (Fertility Research Center, Maria Medical Foundation)
Lim, Jin Ho (Fertility Research Center, Maria Medical Foundation)
Publication Information
Clinical and Experimental Reproductive Medicine / v.41, no.1, 2014 , pp. 9-14 More about this Journal
Abstract
Objective: The aim of this study was to evaluate the efficiency of the intracytoplasmic morphologically selected sperm injection (IMSI) technique compared with conventional ICSI and previous ICSI attempts in oligo-astheno-teratozoospermia (OAT) patients. Methods: The sperms were selected under high magnification ($6,600{\times}$) and used to induce fertilization in previous ICSI patients by IMSI. These results were compared with previous conventional ICSI cycles in patients with OAT infertility. Results: These results demonstrated no significant difference in the fertilization rate between IMSI and previous ICSI cycles (67.7% vs. 65.0%). However, the pregnancy and implantation rates with IMSI were significantly higher than those of the ICSI cycles (33.3% vs. 12.5% and 14.6% vs. 5.4%, respectively; p<0.05). The miscarriage rate among pregnant patients (18.2% vs. 37.5%) showed no statistically significant difference between groups. Conclusion: Compared to conventional ICSI, this study found that IMSI increased the IVF-ET success rates in patients with OAT.
Keywords
High magnification; Intracytoplasmic sperm injection; Intracytoplasmic morphologically selected sperm injection; Oligo-astheno-teratozoospermia;
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