Identification of Gene-based Potential Biomarkers for Cephalexin-induced Nephrotoxicity in Mice |
Park, Han-Jin
(Toxicogenomics Team, Korea Institute of Toxicology)
Oh, Jung-Hwa (Toxicogenomics Team, Korea Institute of Toxicology) Hwang, Ji-Yoon (Toxicogenomics Team, Korea Institute of Toxicology) Lim, Jung-Sun (Toxicogenomics Team, Korea Institute of Toxicology) Jeong, Sun-Young (Toxicogenomics Team, Korea Institute of Toxicology) Kim, Yong-Bum (Clinical Pathology Team, Korea Institute of Toxicology) Yoon, Seok-Joo (Toxicogenomics Team, Korea Institute of Toxicology) |
1 | Tune, B.M. et al. Cephalosporin and Carbacephem nephrotoxicity. Biochem. Phamarcol. 51(4), 557-561 (1996) DOI ScienceOn |
2 | Tennant, R.W. The National Center for Toxicogenomics: using new technologies to inform mechanistic toxicology. Environ. Health Perspect. 110(1), A8-A10 (2002) DOI |
3 | Bulera, S.J. et al. RNA expression in the early characterization of hepatotoxicants in Wistar rats by highdensity DNA microarrays. Hepatology 33(5), 1239-1258 (2001) DOI ScienceOn |
4 | Wu, Y.J. et al. The chemoprotective agent N-acetylcysteine blocks cisplatin-induced apoptosis through caspase signaling pathway. J. Pharmacol. Exp. Ther. 312(2), 424-431 (2005) DOI ScienceOn |
5 | Kharasch, E.D. et al. Gene expression profiling of nephrotoxicity from the sevoflurane degradation product fluoromethyl-2, 2-difluoro-1-(trifluoromethyl) vinyl ether ('compound A') in rats. Toxicol. Sci. 90(2), 419-431 (2006) DOI |
6 | Davis, J.W. 2nd et al. Quantitative gene expression analysis in a nonhuman primate model of antibioticinduced nephrotoxicity. Toxicol. Appl. Pharmacol. 200(1), 16-26 (2004) DOI ScienceOn |
7 | Burczynski, M.E. et al. Toxicogenomics-based discrimination of toxic mechanism in HepG2 human hepatoma cells. Toxicol. Sci. 58(2), 399-415 (2000) DOI ScienceOn |
8 | You, G. The role of organic ion transporters in drug disposition: an update. Curr Drug. Metab. 5(1), 55-62 (2004) DOI ScienceOn |
9 | Gentry, L.O. Cephalosporins in urinary tract infection. Drugs 34(2), 154-163(1987) |
10 | Lettieri, T. Recent Applications of DNA microarray technology to toxicology and ecotoxicology. Environ. Health Perspect. 114(1), 4-9 (2006) |
11 | Tune, B.M. Renal tubular transport and nephrotoxicity of -lactam antibiotics: structure-activity relationships. Minor Electrolyte Metab. 20(4), 221-231 (1994) |
12 | Goldstein, R.S. et al. Biochemical mechanisms of cephaloridine nephrotoxiciy. Life Sci. 42(19), 1809- 1816 (1988) DOI ScienceOn |
13 | Han, W.K. et al. Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury. Kidney Int. 62(1), 237-244 (2002) DOI ScienceOn |
14 | Nishiyama, A. & Abe, Y. Molecular Mechanisms and Therapeutic Strategies of Chronic Renal Injury: Renoprotective Effects of Aldosterone Blockade. J. Pharmacol. Sci. 100(1), 9-16 (2006) DOI ScienceOn |
15 | Morey, M.S. et al. Modulation of the Ras/MAPK signaling pathway by the redoxfunction of selenoproteins in Drosophila melanogaster. Develop. Biol. 238 (1), 145-156 (2001) DOI ScienceOn |
16 | Hamadeh, H.K. et al. Gene expression analysis reveals chemical-specific profiles. Toxicol. Sci. 67(2), 219-231 (2002) DOI ScienceOn |
17 | Duarte, C.G. & Preuss, H.G. Assessment of renal function glomerular and tubular. Clin. Lab. Med. 13 (1), 33-52 (1993) |
18 | Barza, M. The nephrotoxicity of cephalosporins: An overview. J Infect Dis. 137, 60-73(1978) DOI |
19 | Vaidya, V.S. et al. Role of tissue repair in survival from s-(1, 2-dichlorovinyl)-L-cysteine-induced acute renal tubular necrosis in the mouse. Toxicol. Sci. 74 (1), 215-27 (2003) DOI ScienceOn |
20 | Gao, B. STATs and liver disease. Cell Mol. Immunol. 2(2), 92-100 (2005) |
21 | Ichimura, T. et al. Kidney injury molecule-1: a tissue and urinary biomarker for nephrotoxicant-induced renal injury. Am. J. Physiol. Renal Physiol. 286(3), 552-563(2004) DOI ScienceOn |
22 | Thukral, S.K. et al. Prediction of nephrotoxicant action and identification of candidate toxicity-related biomarkers. Toxicol. Pathol. 33(3), 343-55 (2005) DOI |
23 | Tune, B.M. The nephrotoxicity of cephalosporin antibiotics. Structure-activity relationships. Comments Toxicol. 1, 145-170 (1986) |
24 | Afshari, C.A. et al. Application of complementary DNA microarray technology to carcinogen identification, toxicology, and drug safety evaluation. Cancer Res. 59(19), 4759-4760 (1999) |
25 | Nishimura, H. et al. Experimental evaluation of a new antibiotic, Cephalexin (Lilly), a derivative of cephalosporin C. 1. Antimicrobial action in vitro and in vivo and organ distribution following oral administration in mice. Saishin Igaku. 24(8), 1756-1766 (1969) |
26 | Amin, R.P. et al. Identification of putative gene based markers of renal toxicity. Environ. Health Perspect. 112(4), 465-479 (2004) DOI ScienceOn |
27 | Eisen, M.B. et al. Cluster analysis and display of genome-wide expression patterns. Proc. Natl. Acad. Sci. U S A. 95(25), 14863-14868 (1998) |