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A Case of Fahr Disease with Mild Cognitive Impairment and Hyperkinesia  

Yoon, Young-shin (Department of Neurology, Cognitive and Neurodegenerative Disorder Clinic, Ewha Womans University Medical Center, Ewha Womans University School of Medicine)
Kang, Hee-Jin (Department of Neurology, Cognitive and Neurodegenerative Disorder Clinic, Ewha Womans University Medical Center, Ewha Womans University School of Medicine)
Kim, Jung-Eun (Department of Neurology, Cognitive and Neurodegenerative Disorder Clinic, Ewha Womans University Medical Center, Ewha Womans University School of Medicine)
Kim, Bum-Sahn (Department of Nuclear Medicine, Cognitive and Neurodegenerative Disorder Clinic, Ewha Womans University Medical Center, Ewha Womans University School of Medicine)
Park, Kee-Duk (Department of Neurology, Cognitive and Neurodegenerative Disorder Clinic, Ewha Womans University Medical Center, Ewha Womans University School of Medicine)
Choi, Kyoung-Gyu (Department of Neurology, Cognitive and Neurodegenerative Disorder Clinic, Ewha Womans University Medical Center, Ewha Womans University School of Medicine)
Jeong, Jee-H. (Department of Neurology, Cognitive and Neurodegenerative Disorder Clinic, Ewha Womans University Medical Center, Ewha Womans University School of Medicine)
Publication Information
Dementia and Neurocognitive Disorders / v.9, no.2, 2010 , pp. 50-54 More about this Journal
Abstract
A 66-yr-old woman presented with progressive cognitive decline and mild hyperkinetic motor symptoms. Neuropsychological evaluation revealed impairment of memory and frontal executive functions with normal activities of daily living, indicating a mild cognitive impairment. Brain imaging showed extensive calcification involving bilateral basal ganglia, thalamus, occipital cortex and cerebellum consistent with Fahr disease. FDG-PET showed diffuse glucose hypometabolism in bilateral fronto-temporo-parietal cortices, suggesting the disruption of frontal subcortical circuit to be probably associated with the cognitive impairment of the patient.
Keywords
Fahr disease; Mild cognitive impairment; PET;
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