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Dexmedetomidine for Repeated Sedation in Pediatric Sedation During Consecutive Radiation Therapy  

Kim, Eun-Jung (Department of Anesthesiology and Pain Medicine, Pusan National University School of Medicine)
Baek, Seung-Hoon (Department of Anesthesiology and Pain Medicine, Pusan National University School of Medicine)
Byeon, Gyeong-Jo (Department of Anesthesiology and Pain Medicine, Pusan National University School of Medicine)
Woo, Mi-Na (Department of Dental Anesthesia and Pain Medicine, School of Dentistry, Pusan National University)
Publication Information
Journal of The Korean Dental Society of Anesthesiology / v.14, no.4, 2014 , pp. 221-225 More about this Journal
Abstract
External beam radiotherapy (EBRT) causes anxiety and claustrophobia in pediatric patients. To provide exact figures and radiation amounts, an appropriate sedation or anesthesia can be supplied. Alpha 2 agonist dexmedetomidine has been used for sedation and anesthesia in pediatric imaging. Dexmedetomidine has an advantage because it has minimal respiratory depression and no direct effects on myocardial function. We report repeated sedation with dexmedetomidine for 33 consecutive radiation therapies in 5 years old children.
Keywords
Dexmedetomidine; Radiotherapy; Sedation;
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1 Harris EA. Sedation and anesthesia options for pediatric patients in the radiation oncology suite. Int J Pediatr 2010; 2010: 870921.
2 Shukry M, Ramadhyani U. Dexmedetomidine as the primary sedative agentfor brain radiation therapy in a 21-month old child. Paediatr Anaesth 2005; 15: 241-2.   DOI   ScienceOn
3 Fortney JT, Halperin EC, Hertz CM, Schulman SR. Anesthesia for pediatric external beam radiation therapy. Int J Radiat Oncol Biol Phys 1999; 44: 587-91.   DOI   ScienceOn
4 Koroglu A, Demirbilek S, Teksan H, Sagir O, But AK, Ersoy MO. Sedative, haemodynamic and respiratory effects of dexmedetomidine in children undergoing magnetic resonance imaging examination: preliminary results. Br J Anaesth 2005; 94: 821-4.   DOI   ScienceOn
5 Hsu YW, Cortinez LI, Robertson KM, Keifer JC, Sum-Ping ST, Moretti EW, et al. Dexmedetomidine pharmacodynamics: part I: crossover comparison of the respiratory effects of dexmedetomidine and remifentanil in healthy volunteers. Anesthesiology 2004; 101: 1066-76.   DOI   ScienceOn
6 Edge WG, Morgan M. Ketamine and pediatric radiotherapy. Anaesth Intensive Care 1977; 5: 153-6.
7 Mahmoud M, Gunter J, Donnelly LF, Wang Y, Nick TG, Sadhasivam S. A comparison of dexmedetomidine with propofol for magnetic resonance imaging sleep studies in children. Anesth Analg 2009; 109: 745-53.   DOI   ScienceOn
8 Heard CM, Joshi P, Johnson K. Dexmedetomidine for pediatric MRI sedation: a review of a series of cases. Pediatr Anaesth 2007; 17: 888-92.   DOI   ScienceOn
9 Siddappa R, Riggins J, Kariyanna S, Calkins P, Rotta AT. High-dose dexmedetomidine sedation for pediatric MRI. Pediatr Anesth 2011; 21: 153-8.   DOI   ScienceOn
10 Bejian S, Valasek C, Nigro JJ, Cleveland DC, Willis BC. Prolonged use of dexmedetomidine in the paediatric cardiothoracic intensive care unit. Cardiol Young 2009; 19: 98-104.   DOI   ScienceOn
11 Reiter PD, Pietras M, Dobyns EL. Prolonged dexmedetomidine infusions in critically ill infants and children. Indian Pediatr 2009; 46: 767-73.
12 Tellor BR, Arnold HM, Micek ST, Kollef MH. Occurrence and predictors of dexmedetomidine infusion intolerance and failure. Hosp Pract (Minneap) 2012; 40: 186-92.   DOI   ScienceOn
13 Mason KP, Zurakowski D, Zgleszewski SE, Robson CD, Carrier M, Hickey PR, et al. High dose dexmedetomidine as the sole sedative for pediatric MRI. Paediatr Anaesth 2008; 18: 403-11.   DOI   ScienceOn