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The Results of Postoperative Radiotherapy for Early Stage Endometrial Carcinoma  

Kang Min-Kyu (Departments of Radiation Oncology and Samsung Medical Center, Sungkyunkwan University School of Medicine)
Park Won (Departments of Radiation Oncology and Samsung Medical Center, Sungkyunkwan University School of Medicine)
Lee Jeong-Won (Departments of Obstetrics & Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine)
Kim Byounq-Gie (Departments of Obstetrics & Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine)
Bae Duk-Soo (Departments of Obstetrics & Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine)
Lee Je-Ho (Departments of Obstetrics & Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine)
Lee Ki-Heon (Department of Obstetrics & Gynecology, Cheil General Hospital & Women's Healthcare Center, Sungkyunkwan University School of Medicine)
Lim Kyung-Taek (Department of Obstetrics & Gynecology, Cheil General Hospital & Women's Healthcare Center, Sungkyunkwan University School of Medicine)
Kim Tae-Jin (Department of Obstetrics & Gynecology, Cheil General Hospital & Women's Healthcare Center, Sungkyunkwan University School of Medicine)
Seong Seok-Ju (Department of Obstetrics & Gynecology, Cheil General Hospital & Women's Healthcare Center, Sungkyunkwan University School of Medicine)
Park Chong-Taik (Department of Obstetrics & Gynecology, Cheil General Hospital & Women's Healthcare Center, Sungkyunkwan University School of Medicine)
Lee Jeong-Eun (Departments of Radiation Oncology and Samsung Medical Center, Sungkyunkwan University School of Medicine)
Huh Seung-Jae (Departments of Radiation Oncology and Samsung Medical Center, Sungkyunkwan University School of Medicine)
Publication Information
Radiation Oncology Journal / v.24, no.2, 2006 , pp. 116-122 More about this Journal
Abstract
Purpose: To determine treatment policy for early stage endometrial carcinoma, we analyzed the results of postoperative radiotherapy. Materials and Methods: From Oct. 1994 to Aug. 2002, 42 patients with FIGO stage I endometrial carcinoma received postoperative radiotherapy. All patients received curative surgery and pelvic lymph node dissection was done in 25 patients. Based on the FIGO staging system, 3 were at stage IA, 21 were at stage IB and 18 were at stage IC. Histologically, there were 14 grade 1, 16 grade 2, and 12 grade 3. Nineteen patients received intracavitary brachytherapy and 23 patients did whole pelvic radiotherapy. The median period of follow-up was 41 months (22 to 100 months). Results: Five-year overall survival, disease-free survival, local control, and regional control rates of all patients were 85.0%, 87.9%, 100%, and 97.5%, respectively. All failures were distant metastases in 5 patients and two patients had simultaneous regional recurrences. There was no intrapelvic failure in patients who received intracavitary radiotherapy. Grade 3 chronic complications were found in 1 patient (4.3%), who received whole pelvic radiotherapy. Conclusion: We achieved high rates of loco-regional control and survival by curative surgery and post-operative radiotherapy. However, we need to select the type of radiotherapy based on the risk factors for recurrence to reduce the treatment-related complication.
Keywords
Endometrial carcinoma; Surgery; Postoperative radiotherapy;
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