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Effectiveness of Cervical Chuna Manipulative Treatment (CCMT) in Treating Peripheral Facial Paralysis: A Systematic Review and Meta-Analysis

말초 안면신경마비에 대한 경추 교정기법의 효과 체계적 문헌고찰 및 메타 분석

  • Jinyeong Hong (Department of Acupuncture and Moxibustion Medicine, College of Korean Medicine, Sangji University) ;
  • Jin-woo Suh (Department of Neuropsychiatry of Korean Medicine, College of Korean Medicine, Sangji University) ;
  • Dong Hyuk Lee (Department of Anatomy, College of Korean Medicine, Sangji University) ;
  • Yeonju Woo (Department of Physiology, College of Korean Medicine, Sangji University) ;
  • Bo-In Kwon (Department of Pathology, College of Korean Medicine, Sangji University) ;
  • Kyoungsong Song (KS Koreaan Medical Clinic) ;
  • Seojung Ha (Department of Acupuncture and Moxibustion Medicine, College of Korean Medicine, Sangji University) ;
  • Joo-Hee Kim (Department of Acupuncture and Moxibustion Medicine, College of Korean Medicine, Sangji University)
  • 홍진영 (상지대학교 한의과대학 침구의학과) ;
  • 서진우 (상지대학교 한의과대학 한방신경정신과) ;
  • 이동혁 (상지대학교 한의과대학 해부학과) ;
  • 우연주 (상지대학교 한의과대학 생리학과) ;
  • 권보인 (상지대학교 한의과대학 병리학과) ;
  • 송경송 (경송한의원) ;
  • 하서정 (상지대학교 한의과대학 침구의학과) ;
  • 김주희 (상지대학교 한의과대학 침구의학과)
  • Received : 2024.05.31
  • Accepted : 2024.06.18
  • Published : 2024.06.30

Abstract

Objectives This study aims to evaluate the effectiveness of cervical chuna manipulative treatment (CCMT) in patients with peripheral facial paralysis (PFP). Methods We conducted a comprehensive search of MEDLINE, CENTRAL, EMBASE, KMbase, OASIS and ScienceOn, and CNKI for randomized controlled trials (RCTs) comparing CCMT for PFP up to April 25, 2024. Risk of Bias was assessed using the Cochrane RoB tool. Results Among the 462 studies retrieved, 5 RCTs with a total of 340 patients were included in the systematic review. Of these, 4 RCTs that reported the total effectiveness rate as the primary outcome were included in the meta-analysis. CCMT combined with acupuncture showed significant improvement in total effectiveness rate compared to acupuncture alone (Relative Ratio [RR] 1.14, 95% CI 1.04 to 1.26, I2=49, P<0.008). However, the included studies had some limitations including uncertain risk of bias and short follow-up periods. Conclusions CCMT may be an effective treatment for PFP. Due to the low quality of evidence from the included studies, high-quality, well-designed RCTs are needed to further verify the effectiveness and safety of CCMT.

Keywords

Acknowledgement

This research was supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (grant number : RS-2021-KH109727(HF21C0011)) and Regional Innovation Strategy (RIS) through the National Research Foundation of Korea(NRF) funded by the Ministry of Education(MOE)(2022RIS-005).

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