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대한천식알레르기학회 설하면역요법 진료지침

The Korean Academy of Asthma Allergy and Clinical Immunology guidelines for sublingual immunotherapy

  • 류광희 (성균관대학교 의과대학 삼성서울병원 이비인후과) ;
  • 지혜미 (차의과학대학교 분당차병원 소아청소년과) ;
  • 이화영 (가톨릭대학교 의과대학 서울성모병원 내과) ;
  • 강성윤 (가천대학교 의과대학 가천대길병원 호흡기알레르기내과) ;
  • 김경훈 (서울대학교 의과대학 분당서울대학교병원 소아청소년과) ;
  • 김주희 (경희대학교 의과대학 소아청소년과학교실) ;
  • 박경희 (연세대학교 의과대학 내과학교실) ;
  • 박소영 (중앙대학교 의과대학 내과학교실) ;
  • 성명순 (순천향대학교 구미병원 소아청소년과) ;
  • 이영수 (아주대학교 의과대학 알레르기내과학교실) ;
  • 양은애 (가톨릭대학교 의과대학 대전성모병원 소아청소년과) ;
  • 민진영 (경희대학교 의과대학 경희대학교병원 이비인후과) ;
  • 하은교 (한림대학교 의과대학 강남성심병원 소아청소년과) ;
  • 이상민 (가천대학교 의과대학 가천대길병원 호흡기알레르기내과) ;
  • 이용원 (가톨릭관동대학교 의과대학 국제성모병원 알레르기내과/의학산업연구센터) ;
  • 정은희 (충남대학교 의과대학 소아청소년과학교실) ;
  • 최선희 (경희대학교 강동병원 소아청소년과) ;
  • 고영일 (전남대학교 의과대학 전남대학교병원 알레르기내과) ;
  • 김선태 (가천대학교 의과대학 길병원 이비인후과) ;
  • 남동호 (아주대학교 의과대학 알레르기내과학교실) ;
  • 박중원 (연세대학교 의과대학 내과학교실) ;
  • 심정연 (성균관대학교 의과대학 강북삼성병원 소아청소년과) ;
  • 안영민 (장스 소아과) ;
  • 한만용 (차의과학대학교 분당차병원 소아청소년과) ;
  • 최정희 (한림대학교 동탄성심병원 호흡기알레르기내과) ;
  • 신유섭 (아주대학교 의과대학 알레르기내과학교실) ;
  • 한두희 (서울대학교 의과대학 이비인후과학교실) ;
  • 대한천식알레르기학회 면역요법/알레르겐연구팀 (대한천식알레르기학회)
  • Gwanghui Ryu (Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Hye Mi Jee (Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine) ;
  • Hwa Young Lee (Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Sung-Yoon Kang (Division of Pulmonology and Allergy, Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University College of Medicine) ;
  • Kyunghoon Kim (Department of Pediatrics, Seoul National University Bundang Hospital, Seoul National University College of Medicine) ;
  • Ju Hee Kim (Department of Pediatrics, Kyung Hee University School of Medicine) ;
  • Kyung Hee Park (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • So-Young Park (Department of Internal Medicine, Chung-Ang University College of Medicine) ;
  • Myong Soon Sung (Department of Pediatrics, Soonchunhyang University Gumi Hospital) ;
  • Youngsoo Lee (Department of Allergy and Clinical Immunology, Ajou University School of Medicine) ;
  • Eun-Ae Yang (Department of Pediatrics, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Jin-Young Min (Department of Otorhinolaryngology-Head & Neck Surgery, Kyung Hee University Hospital, Kyung Hee University College of Medicine) ;
  • Eun Kyo Ha (Department of Pediatrics, Kangnam Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Sang Min Lee (Division of Pulmonology and Allergy, Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University College of Medicine) ;
  • Yong Won Lee (Division of Allergy & Clinical Immunology, Department of Internal Medicine, Center for Health Policy Research, Catholic Kwandong University College of Medicine, International St. Mary's Hospital) ;
  • Eun Hee Chung (Department of Pediatrics, Chungnam National University School of Medicine) ;
  • Sun Hee Choi (Department of Pediatrics, Kyung Hee University Hospital at Gangdong) ;
  • Young-Il Koh (Department of Allergy and Clinical Immunology, Chonnam National University Hospital, Chonnam National University Medical School) ;
  • Seon Tae Kim (Department of Otolaryngology-Head & Neck Surgery, Gachon University Gil Medical Center, Gachon University College of Medicine) ;
  • Dong-Ho Nahm (Department of Allergy and Clinical Immunology, Ajou University School of Medicine) ;
  • Jung Won Park (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Jung Yeon Shim (Department of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) ;
  • Young Min An (Jang's Pediatrics) ;
  • Man Yong Han (Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine) ;
  • Jeong-Hee Choi (Department of Pulmonology and Allergy, Hallym University Dongtan Sacred Heart Hospital) ;
  • Yoo Seob Shin (Department of Allergy and Clinical Immunology, Ajou University School of Medicine) ;
  • Doo Hee Han (Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine) ;
  • Korean Academy of Asthma Allergy and Clinical Immunology (KAAACI) Allergen Immunotherapy and Allergen Working Group (Korean Academy of Asthma Allergy and Clinical Immunology (KAAACI))
  • 투고 : 2023.10.24
  • 심사 : 2024.02.27
  • 발행 : 2024.07.30

초록

Allergen immunotherapy (AIT) has been used for over a century and has been demonstrated to be effective in treating patients with various allergic diseases. AIT allergens can be administered through various routes, including subcutaneous, sublingual, intra-lymphatic, oral, or epicutaneous routes. Sublingual immunotherapy (SLIT) has recently gained clinical interest, and it is considered an alternative treatment for allergic rhinitis (AR) and asthma. This review provides an overview of the current evidence-based studies that address the use of SLIT for treating AR, including (1) mechanisms of action, (2) appropriate patient selection for SLIT, (3) the current available SLIT products in Korea, and (4) updated information on its efficacy and safety. Finally, this guideline aims to provide the clinician with practical considerations for SLIT.

키워드

과제정보

이 면역치료 진료지침은 대한천식알레르기학회의 연구비 지원을 받아서 제작되었습니다. 지침 제작에 참여하신 대한천식알레르기학회 면역요법/알레르겐연구팀의 모든 선생님들께 감사를 드립니다. 이 논문은 Allergy Asthma Immunol Res (AAIR) 잡지에 1차 출판된 논문(https://doi.org/10.4168/aair.2024.16.1.9)의 2차 출판물로 AAIR/AARD 잡지 편집장과 저자들의 2차 출판 허가를 받았습니다.

참고문헌

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