Journal of Oriental Neuropsychiatry (동의신경정신과학회지)

The Korean Society of Oriental Neuropsychiatry (대한한방신경정신과학회)
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A Review of Clinical Studies on Depression Caused by Parkinson's Disease in Traditional Korean Medicine

파킨슨병으로 인한 우울증의 한의 임상연구 고찰

  • Jeongwon Kim (College of Korean Medicine, Woosuk University) ;
  • Taegwang Nam (College of Korean Medicine, Woosuk University) ;
  • Anna Kim (KM Data Division, Korea Institute of Oriental Medicine) ;
  • Yongtaek Oh (Department of Diagnostics, College of Korean Medicine, Woosuk University)
  • 김정원 (우석대학교 한의과대학) ;
  • 남태광 (우석대학교 한의과대학) ;
  • 김안나 (한국한의학연구원 한의약데이터부) ;
  • 오용택 (우석대학교 한의과대학 진단학교실)
  • Received : 2024.08.22
  • Accepted : 2024.09.23
  • Published : 2024.09.30
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Abstract

Objectives: Parkinson's disease is a degenerative neurological disorder caused by dopamine neuron damage, leading to various motor and non-motor symptoms, including depression. While several clinical studies on Traditional Korean Medicine (TKM) have addressed this issue, no comprehensive review has been conducted. This study aimed to summarize and analyze TKM treatments for depression associated with Parkinson's disease. Methods: This study reviewed research focused on treatment of Parkinson's-related depression, particularly examining traditional therapies such as acupuncture and herbal medicine. Data on treatment methods were analyzed to compare approaches of control and experimental groups. Specific use of acupuncture points and other TKM treatments was analyzed. Results: Out of 57 studies, 17 involving 649 participants were selected. Various treatment methods were evaluated, primarily using the Unified Parkinson's Disease Rating Scale (UPDRS). Studies predominantly focused on acupuncture targeting specific points (such as LI 4, GB 20, and ST 36) and the use of various herbal medicine combinations. Conclusions: Of the 17 studies, 13 focused on effects of acupuncture, suggesting that acupuncture might play a significant role in alleviating depression associated with Parkinson's disease. Specifically, the use of acupuncture points such as LI 4, GB 20, and ST 36 showed potential therapeutic effects. Additionally, 13 studies demonstrated that TKM could significantly alleviate depression, indicating the potential for an integrative approach combining Eastern and Western therapies. Herbal medicine and Qigong dance therapy also showed promising effects in improving depression.

Keywords

Acknowledgement

This work was supported by the Korea Institute of Oriental Medicine (grant number KSN1923111) and the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) (No. RS-2023-00254007).

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