Journal of Integrative Natural Science (통합자연과학논문집)

The Basic Science Institute Chosun University (조선대학교 기초과학연구원)
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Analysis of Manufacturing Conditions Affecting the DropletSize of Ethyl Cellulose Nanoparticles

에틸 셀룰로오스 나노 파티클 입자 사이즈에 영향을 주는제조 조건의 분석

  • Jong Hwan Bae (Division of Chemistry and Cosmetics, Dongduk Women's University) ;
  • Byung Suk Jin (Division of Chemistry and Cosmetics, Dongduk Women's University)
  • 배종환 (동덕여자 대학교 화학 화장품 학부) ;
  • 진병석 (동덕여자 대학교 화학 화장품 학부)
  • Received : 2024.08.19
  • Accepted : 2024.08.29
  • Published : 2024.09.30
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Abstract

Using the design of experiments (DOE), factors affecting the droplet size of ethyl cellulose (EC) nanoparticles in the manufacturing process were analyzed to optimize process conditions. The concentration of EC dissolved in solvent (acetone or ethanol), the mixing ratio of the EC solution to distilled water, and sonication power were selected as the main variables affecting the droplet size of the nanoparticles. The effect of these variables on droplet size was examined through the signal-to-noise (S/N) ratios of the Taguchi method and ANOVA analysis. Sonication power in the acetone solvent and EC solution concentration in the ethanol solvent were identified as the most influential factors on nanoparticle size.

Keywords

Acknowledgement

본 연구는 2023년 동덕여자대학교 학술 연구비 지원에 의해 이루어졌으며 이에 감사드립니다.

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