Journal of Chest Surgery

The Korean Society for Thoracic and Cardiovascular Surgery (대한심장혈관흉부외과학회)
권호 표지
DOI QR코드

DOI QR Code

Malignant Solitary Fibrous Tumor of the Mediastinum with Multiple Recurrences and a Rare Metastasis to the Thyroid Gland: A Case Report

  • Ju Sik Yun (Department of Thoracic and Cardiovascular Surgery, Chonnam National University Hwasun Hospital, Chonnam National University School of Medicine) ;
  • Sang Yun Song (Department of Thoracic and Cardiovascular Surgery, Chonnam National University Hwasun Hospital, Chonnam National University School of Medicine) ;
  • Kook Joo Na (Department of Thoracic and Cardiovascular Surgery, Chonnam National University Hwasun Hospital, Chonnam National University School of Medicine) ;
  • Sang Gi Oh (Department of Thoracic and Cardiovascular Surgery, Chonnam National University Hospital, Chonnam National University School of Medicine) ;
  • Haein Ko (Department of Thoracic and Cardiovascular Surgery, Chonnam National University Hospital, Chonnam National University School of Medicine)
  • Received : 2024.01.08
  • Accepted : 2024.02.05
  • Published : 2024.09.05
Download PDF
⟨ Previous Next ⟩

Abstract

Solitary fibrous tumors (SFTs) are rare neoplasms arising from mesenchymal cells. Although most SFTs are benign, rare cases of metastasis have been reported at various sites. Complete surgical resection is the mainstay of treatment for both primary and recurrent or metastatic SFTs. Herein, we present a case of an SFT initially identified in the anterior mediastinum that later developed multiple metastases, even to the thyroid gland. The patient underwent repeated surgical resection and is currently being followed up in an outpatient setting.

Keywords

References

  1. Martin-Broto J, Mondaza-Hernandez JL, Moura DS, Hindi N. A comprehensive review on solitary fibrous tumor: new insights for new horizons. Cancers (Basel) 2021;13:2913. https://doi.org/10.3390/cancers13122913
  2. Guo W, Xiao HL, Jiang YG, et al. Retrospective analysis for thirty-nine patients with solitary fibrous tumor of pleura and review of the literature. World J Surg Oncol 2011;9:134. https://doi.org/10.1186/1477-7819-9-134
  3. Reisenauer JS, Mneimneh W, Jenkins S, et al. Comparison of risk stratification models to predict recurrence and survival in pleuropulmonary solitary fibrous tumor. J Thorac Oncol 2018;13:1349-62. https://doi.org/10.1016/j.jtho.2018.05.040
  4. Salas S, Resseguier N, Blay JY, et al. Prediction of local and metastatic recurrence in solitary fibrous tumor: construction of a risk calculator in a multicenter cohort from the French Sarcoma Group (FSG) database. Ann Oncol 2017;28:1979-87. https://doi.org/10.1093/annonc/mdx250
  5. O'Neill AC, Tirumani SH, Do WS, et al. Metastatic patterns of solitary fibrous tumors: a single-institution experience. AJR Am J Roentgenol 2017;208:2-9. https://doi.org/10.2214/AJR.16.16662
  6. Ricciuti B, Metro G, Leonardi GC, et al. Malignant giant solitary fibrous tumor of the pleura metastatic to the thyroid gland. Tumori 2016;102(2_suppl):S16-21. https://doi.org/10.5301/tj.5000514
  7. Kovacs T, Waxman J. Recurrence of a malignant solitary fibrous tumor of the pleura 17 years after primary tumor resection: a case report. Respir Med Case Rep 2019;28:100895. https://doi.org/10.1016/j.rmcr.2019.100895
  8. Park CK, Lee DH, Park JY, Park SH, Kwon KY. Multiple recurrent malignant solitary fibrous tumors: long-term follow-up of 24 years. Ann Thorac Surg 2011;91:1285-8. https://doi.org/10.1016/j.athoracsur.2010.08.074
  9. Park MS, Ravi V, Conley A, et al. The role of chemotherapy in advanced solitary fibrous tumors: a retrospective analysis. Clin Sarcoma Res 2013;3:7. https://doi.org/10.1186/2045-3329-3-7
  10. Bertoglio P, Querzoli G, Kestenholz P, et al. Surgery for solitary fibrous tumors of the pleura: a review of the available evidence. Cancers (Basel) 2023;15:4166. https://doi.org/10.3390/cancers15164166