The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)

The Society of Korean Medicine Ophthalmology, Otolaryngology & Dermatology (대한한방안이비인후피부과학회)
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A Systemic Review and Meta-Analysis of Herbal Medicine Treatment for Acute Pharyngitis : Based on Chinese Articles

급성인두염의 한약 치료에 대한 체계적 문헌 고찰 및 메타분석 : 중국 논문을 중심으로

  • Young-Eun Lee (Dep. of Korean Medicine Ophthalmology & Otolaryngology & Dermatology, Daegu Hanny University) ;
  • Ji-One Im (Dep. of Korean Medicine Ophthalmology & Otolaryngology & Dermatology, Daegu Hanny University) ;
  • Ji-Young Choi (Dep. of Korean Medicine Ophthalmology & Otolaryngology & Dermatology, Daegu Hanny University) ;
  • Seon-Young Jee (Dep. of Korean Medicine Ophthalmology & Otolaryngology & Dermatology, Daegu Hanny University) ;
  • Min Hwangbo (Dep. of Korean Medicine Ophthalmology & Otolaryngology & Dermatology, Daegu Hanny University)
  • 이영은 (대구한의대 한방병원 안이비인후피부과) ;
  • 임지원 (대구한의대 한방병원 안이비인후피부과) ;
  • 최지영 (대구한의대 한방병원 안이비인후피부과) ;
  • 지선영 (대구한의대 포항한방병원 안이비인후피부과 ) ;
  • 황보민 (대구한의대 한방병원 안이비인후피부과)
  • Received : 2024.07.05
  • Accepted : 2024.08.01
  • Published : 2024.08.25
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Abstract

Objectives : The purpose of this study is to investigate the effectiveness and safety of herbal medicine treatment for acute pharyngitis. Methods : 2 databases(Wangfang Med Online, CNKI) were used to search Randomized Controlled Trials(RCTs) that used herbal medicine treatment for acute pharyngitis, which were published from January 2007 until April 2024. Results : 9 RCTs were selected in this study, and all studies compared herbal medicine alone treatment with western medicine alone treatment. The most frequently used medicine was Toxin-removing medicinal(淸熱解毒藥). Platycodonis Radix(桔梗) was the most frequently used herb. Meta-analysis of nine studies showed that the Total Effective Rate(TER) of treatment group was statistically higher than that of control group(RR:1.12, 95% CI:1.06 to 1.19, p<0.00001, I2=22%). Meta-analysis of 3 studies showed that the total symptom score of treatment group statistically improved than that of control group(MD: -1.00, 95% CI: -1.30 to -0.71, p<0.00001, I2=0%). Mild adverse events such as anorexia were identified in 4 RCTs, but no serious adverse events were reported. Conclusion : Using herbal medicine alone can be more effective and safe in improving acute pharyngitis than using western medicine. But further well-designed studies are needed because heterogeneity between studies existed and the quality of the reports needs to be improved.

Keywords

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