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Discriminative Power of Seoul Cognitive Status Test in Differentiating Subjective Cognitive Decline, Amnestic Mild Cognitive Impairment, and Dementia Based on CERAD-K Standards

  • Hasom Moon (Department of Neurology, Seoul National University Hospital, Seoul National University School of Medicine) ;
  • Eek-Sung Lee (Department of Neurology, Soonchunhyang University Bucheon Hospital) ;
  • Seunghee Na (Department of Neurology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Dayeong An (Happymind Clinic) ;
  • Joon Soo Shin (BeauBrain Healthcare) ;
  • Duk L. Na (Happymind Clinic) ;
  • Hyemin Jang (Department of Neurology, Seoul National University Hospital, Seoul National University School of Medicine)
  • 투고 : 2024.06.03
  • 심사 : 2024.07.08
  • 발행 : 2024.07.31

초록

Background and Purpose: We developed a new digital cognitive assessment called Seoul Cognitive Status Test (SCST), formerly called Inbrain Cognitive Screening Test. The purpose of this study was to validate the clinical utility of the SCST by comparing its scores of those with subjective cognitive decline (SCD), amnestic mild cognitive impairment (aMCI), and dementia diagnosed by the Korean version of the Consortium to Establish a Registry for Alzheimer's Disease Assessment Packet (CERAD-K). Methods: All participants (n=296) who completed the CERAD-K, SCST, and Instrumental Activities of Daily Living tests were included in this study. Total score, cognitive domain scores, and subtest scores of the SCST were compared among the 3 groups (SCD, aMCI, and dementia). Additionally, correlations between SCST and CERAD-K subtests were examined. Results: Cognitive domain scores and total score of the SCST showed significant differences among the three groups, with scores being the highest in the order of SCD, aMCI, and dementia (p<0.001). Most subtests of the SCST also showed higher scores in the order of SCD, aMCI, and dementia (p<0.001). However, SCD and aMCI groups showed no significant differences in scores of the Phonemic Word Fluency Test (p=0.083) or Korean Trail Making Test-Elderly version Part A (p=0.434). Additionally, there was no significant difference in the score of Place Recognition (p=0.274) of the Word-Place Association Test between aMCI and dementia groups. Conclusions: In conclusion, differences in total score, cognitive domain scores, and subtest scores of the SCST among the 3 groups of participants diagnosed using CERAD-K confirm the clinical utility of the SCST for cognitive assessment.

키워드

참고문헌

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