Nuclear Engineering and Technology

  • 제56권7호
  • /
  • Pages.2732-2739
  • /
  • 2024
  • /
  • 1738-5733(pISSN)
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  • 2234-358X(eISSN)
한국원자력학회 (Korean Nuclear Society)
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Radioiodine internal dose coefficients specific for Koreans

  • Tae-Eun Kwon (Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health) ;
  • Yoonsun Chung (Department of Nuclear Engineering, Hanyang University) ;
  • Choonsik Lee (Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health)
  • 투고 : 2023.11.21
  • 심사 : 2024.02.17
  • 발행 : 2024.07.25
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초록

This study developed internal dose coefficients for radioiodine, tailored to the Korean population, by incorporating the Korean biokinetic model along with the Korean S values. The observed differences in dose coefficients for Koreans compared to the International Commission on Radiological Protection (ICRP) reference values noticeably varied depending on physical half-lives of iodine isotopes. For longer-lived isotopes such as I-125 and I-129, significant differences in thyroid dose coefficients were observed, with ratios (Korean/ICRP) from 0.30 to 0.55, indicating that actual doses for Koreans can be considerably lower than those evaluated based on the ICRP data. However, for short-lived iodine isotopes, such as I-131, the thyroid dose coefficients were comparable to the ICRP reference values (ratio = 0.95-0.98). These comparable dose coefficients resulted from the lower thyroidal iodine uptake in the Korean model being almost entirely offset by the higher thyroid self-absorption S values in the Korean phantoms. Additionally, this study delves into the substantial differences in absorbed dose coefficients for non-thyroidal regions and effective dose coefficients, which arose not only from physiological/anatomical variability but also technical differences in phantom design. The use of Korean-specific dose coefficients is advisable particularly in scenarios predicting elevated doses, yielding a more precise and clinically relevant dose assessment.

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과제정보

This research was funded by the intramural research program of the National Institutes of Health (NIH), National Cancer Institute, Division of Cancer Epidemiology and Genetics.

참고문헌

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